Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
DB Fernverkehr + DB Regio Bayern + alex - Die Länderbahn | Karlsruhe Hbf | Hlavní nádraží | Cheapest | |||||
 | Karlsruhe Hbf | Hlavní nádraží | Fastest | |||||
Flixtrain + Flixbus | Karlsruhe Hbf | Prague (Central Bus Station Florenc) | No tags | |||||
DB Fernverkehr + DB Regio Bayern + alex - Die Länderbahn | Karlsruhe Hbf | Hlavní nádraží | No tags | |||||
DB Fernverkehr + DB Regio Südost + Ceske Drahy | Karlsruhe Hbf | Hlavní nádraží | No tags | |||||
| Karlsruhe Hbf | Hlavní nádraží | No tags | |||||
Flixtrain + Flixbus | Karlsruhe Hbf | Prague (Main Station - parking) | No tags | |||||
DB Fernverkehr + DB Regio Bayern + alex - Die Länderbahn | Karlsruhe Hbf | Hlavní nádraží | No tags |
Last refresh of the prices: Yesterday at 7:11 AM CEST.
Compare 2 ways to go from Karlsruhe to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 9 hours 45 minutes and with fares starting at just ₪109, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Karlsruhe and Prague?
Karlsruhe
- A
Karlsruhe Hbf
Bahnhofpl. 1A, 76137 Karlsruhe, Germany - B
Südseite Hauptbahnhof
Hinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
Prague
- A
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia - B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - E
Holešovice
Praha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia - F
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Train Companies
Frequently asked questions about traveling from Karlsruhe to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Karlsruhe to Prague?
The cheapest train tickets from Karlsruhe to Prague start from ₪97. The average price for this train route is around ₪368. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Karlsruhe to Prague?
The average train ride duration from Karlsruhe to Prague is 9h 16m, covering a distance of 281 miles (452 km). The quickest train can get you there in 8h 26m and is operated by Deutsche Bahn.
Which train operators service the Karlsruhe to Prague route?
Several major train operators operate on this route with 11 trains available per day, including services from Deutsche Bahn, Deutsche Bahn EuroCity.
What is the earliest and latest departure time for the train from Karlsruhe to Prague?
The earliest train departs from Karlsruhe to Prague at 6:00am. And the latest train departs at 11:44pm.
What is the best train operator from Karlsruhe to Prague?
According to Busbud customers, the highest-rated train operator on this route is Deutsche Bahn EuroCity, with an average rating of 5.0 out of 5 stars based on 1 reviews.
Which train operator has the best Wi-Fi from Karlsruhe to Prague?
Based on reviews on Busbud, the train operator Deutsche Bahn EuroCity has the best Wi-Fi rating with a score of 5.0.
Which train operator has the most timely service from Karlsruhe to Prague?
According to Busbud traveler reviews, the most timely train operator on this route is Deutsche Bahn EuroCity, with a punctuality rating of 5.0 out of 5 stars.
Which train operator has the cleanest trains from Karlsruhe to Prague?
According to Busbud traveler reviews, the train operator with the cleanest trains on this route is Deutsche Bahn EuroCity, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Prague was searched and found on Aug 8, 2026 with a price of ₪91To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Karlsruhe to Prague, as early as possible.
You can expect to pay from ₪91 to ₪847 for a train ticket from Karlsruhe to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at ₪91 which is on 2026-08-08.
