Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Ceske Drahy + DB Regio Bayern + DB Fernverkehr + SÜWEX | Hlavní nádraží | Mainz Central Train Station | CheapestFastest | |||||
Ceske Drahy + DB Regio Bayern + HLB | Hlavní nádraží | Mainz Central Train Station | No tags | |||||
Ceske Drahy + DB Regio Südost + DB Fernverkehr + S-Bahn Rhein-Main | Hlavní nádraží | Mainz Central Train Station | No tags | |||||
Ceske Drahy + DB Regio Bayern + HLB | Hlavní nádraží | Mainz Central Train Station | No tags | |||||
Ceske Drahy + DB Regio Südost + DB Fernverkehr + S-Bahn Rhein-Main | Hlavní nádraží | Mainz Central Train Station | No tags | |||||
Ceske Drahy + DB Regio Bayern + DB Fernverkehr + SÜWEX | Hlavní nádraží | Mainz Central Train Station | No tags | |||||
Ceske Drahy + DB Regio Südost + DB Fernverkehr + S-Bahn Rhein-Main | Hlavní nádraží | Mainz Central Train Station | No tags | |||||
Ceske Drahy + DB Regio Bayern + DB Fernverkehr + SÜWEX | Hlavní nádraží | Mainz Central Train Station | No tags |
Last refresh of the prices: Yesterday at 11:30 AM CEST.
Compare 2 ways to go from Prague to Mainz
Among the sustainable travel choices, the Bus stands out as a good way to reach Mainz. The journey takes about 11 hours 35 minutes, and with fares starting at just COP 123,898, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Prague and Mainz?
Prague
- A
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia - B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - E
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - F
Holešovice
Praha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia
Train companies
Based on 10 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the ticket access and the departure location but often complained with the Wi‑Fi. Deutsche Bahn ticket prices on this trip start at COP 809,929
Frequently asked questions about travelling from Prague to Mainz by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Prague to Mainz?
The cheapest train tickets from Prague to Mainz start at COP 135,275. The average price for this train route is around COP 532,401. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Prague to Mainz?
The average train trip from Prague to Mainz takes 9h 18m and covers 442 km. The quickest train gets you there in 8h 44m and is operated by Deutsche Bahn.
Which train operators serve the Prague to Mainz route?
Several major train operators serve this route, with 11 trains available per day.
What are the earliest and latest departure times for the train from Prague to Mainz?
The earliest train from Prague to Mainz departs at 6:31am. The latest train departs at 8:47pm.





