Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greyhound Amtrak Station | Gateway Station | Cheapest | ||||
| Train | Greyhound Amtrak Station | Gateway Station | Fastest | ||||
| Train | Greyhound Amtrak Station | Gateway Station | No tags | ||||
| Train | Greyhound Amtrak Station | Gateway Station | No tags | ||||
| Train | Greyhound Amtrak Station | Gateway Station | No tags |
Last refresh of the prices: Today at 8:04 AM EST.
Compare 2 ways to go from Indianapolis to St. Louis
Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 4 hours 20 minutes, and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Indianapolis and St. Louis?
Train companies
Based on 5727 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $92
Frequently asked questions about travelling from Indianapolis to St. Louis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Indianapolis to St. Louis?
The cheapest train tickets from Indianapolis to St. Louis start at $92. The average price for this train route is around $157. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Indianapolis to St. Louis?
The average train trip from Indianapolis to St. Louis takes 16h 58m and covers 371 km. The quickest train gets you there in 14h and is operated by Amtrak.
Which train operators serve the Indianapolis to St. Louis route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Indianapolis to St. Louis?
The earliest train from Indianapolis to St. Louis departs at 6:00am. The latest train departs at 6:25am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to St. Louis was searched and found on Jan 12, 2026 with a price of $138To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to St. Louis, as early as possible.
You can expect to pay from $138 to $665 for a train ticket from Indianapolis to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $150 which is on 2026-01-15.
