Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Jefferson City, MO | Chicago (Union Station), IL | CheapestFastest | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Yesterday at 10:01 PM CST.
Compare 2 ways to go from Jefferson City to Chicago
Among the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 8 hours 11 minutes, and with fares starting at just $71, it presents an excellent value for a comfortable ride.
Train companies
Based on 5598 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $71
Frequently asked questions about travelling from Jefferson City, MO to Chicago by train
How much does a cheap train ticket from Jefferson City to Chicago cost?
The average train ticket price from Jefferson City to Chicago is $85. The best way to find cheap train tickets from Jefferson City to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Jefferson City to Chicago?
A train trip between Jefferson City and Chicago is around 8h 11m, although the fastest train will take about 8h 11m. This is the time it takes to travel the 531 km that separates the two cities.
How many daily trains are there between Jefferson City and Chicago?
The number of trains from Jefferson City to Chicago can differ depending on the day of the week. On average, there are 2. Some trains are direct while others include transferring trains. Simplify your train trip from Jefferson City to Chicago by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Jefferson City to Chicago?
When taking the train from Jefferson City to Chicago, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jefferson City, MO to Chicago was searched and found on Nov 23, 2025 with a price of $67To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jefferson City, MO to Chicago, as early as possible.
You can expect to pay from $67 to $556 for a train ticket from Jefferson City, MO to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-11-23.
What's the cheapest way to go from Jefferson City, MO to Chicago?
The train is the cheapest travel choice for this destinationThe best way to travel between Jefferson City, MO and Chicago is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $85 on average. If you're on a budget, you'll find cheap tickets from $71. If you're looking for the fastest way to get to Chicago, choose the train, as it will take you from Jefferson City, MO to Chicago in about 8h 11m —that's the fastest way to get there!
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