Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Waterloo Station | Gateway Station | Cheapest | ||||
| Train | Waterloo Station | Gateway Station | Fastest | ||||
| Train | Waterloo Station | Gateway Station | No tags | ||||
| Train | Waterloo Station | Gateway Station | No tags | ||||
| Train | Waterloo Station | Gateway Station | No tags |
Last refresh of the prices: Today at 12:21 PM EST.
Get from Waterloo to St. Louis
The journey takes about 16 hours 47 minutes, and with fares starting at just $79, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Waterloo, IN, US and St. Louis?
Train companies
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $79
Frequently asked questions about travelling from Waterloo, IN, US to St. Louis by train
How much does a cheap train ticket from Waterloo to St. Louis cost?
The average train ticket price from Waterloo to St. Louis is $159. The best way to find cheap train tickets from Waterloo to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Waterloo to St. Louis?
A train trip between Waterloo and St. Louis is around 16h 47m, although the fastest train will take about 12h 16m. This is the time it takes to travel the 541 km that separates the two cities.
How many daily trains are there between Waterloo and St. Louis?
The number of trains from Waterloo to St. Louis can differ depending on the day of the week. On average, there are 4. Some trains are direct while others include transferring trains. Simplify your train trip from Waterloo to St. Louis by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Waterloo to St. Louis?
When taking the train from Waterloo to St. Louis, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Waterloo, IN, US to St. Louis was searched and found on Nov 28, 2025 with a price of $196To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Waterloo, IN, US to St. Louis, as early as possible.
You can expect to pay from $196 to $1,290 for a train ticket from Waterloo, IN, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $196 which is on 2025-11-28.
