Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Niagara Frontier Transportation Authority | Florence, SC | ||||
FlixBus + Greyhound | Bus | Niagara Frontier Transportation Authority | Bus station | ||||
Greyhound + FlixBus | Bus | Buffalo (BUF) Airport | Bus station | ||||
 | Bus | Buffalo (BUF) Airport | Florence, SC | ||||
| Bus | Niagara Frontier Transportation Authority | Florence, SC |
Compare 2 ways to travel from Buffalo to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 5 hours 46 minutes and with fares starting at just TRY 7,784, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Florence?
Stops in Buffalo
- B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA - C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling by bus from Buffalo, NY to Florence, SC, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Buffalo to Florence?
The cheapest coach tickets from Buffalo to Florence start from TRY 7,784. The average price for this route is around TRY 10,392. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Buffalo to Florence?
The average bus journey time from Buffalo to Florence is 1d 5h, covering a distance of 604 miles. The fastest bus can take you there in 1d and is operated by FlixBus.
Which bus companies service the Buffalo to Florence route?
What is the earliest and latest departure time for the bus from Buffalo to Florence?
The earliest bus departs from Buffalo to Florence at 05:30. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Buffalo to Florence?
A bus journey from Buffalo to Florence produces an estimated 24.332275000000003 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Buffalo to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12791 reviews.
Which company has the best Wi-Fi from Buffalo to Florence?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Buffalo to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Florence, SC, US was searched and found on 17 Jun 2026 with a price of TRY 5,287To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Florence, SC, US as early as possible.
You can expect to pay from TRY 5,287 to TRY 5,595 for a bus ticket from Buffalo, NY to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at TRY 5,287, which is on 2026-06-17.
What's the cheapest way to go from Buffalo, NY to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
