How do I get from Buffalo to Florence without flying?

You have the option of traveling from one city to the other by either bus or train. Either way you choose, you'll be sure to reach your destination in the most easy and sustainable way. Another option you should consider is using carpooling services, which allow you to share a car ride with other travelers.

How long is the bus trip from Buffalo to Florence?

The travel time from Buffalo to Florence is about 1d 5h, but you can get there in as little as 20h 35m with the quickest bus. This is the time it takes to travel the 601 miles (969 km) that separate the two cities.

How far is Buffalo from Florence?

About 601 miles (969 km) separate Buffalo and Florence.

What are the departure and arrival stations when taking the bus from Buffalo to Florence?

Most of the buses traveling from Buffalo to Florence leave from Buffalo Airport and arrive at Florence Bus Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What is the cheapest way to go from Buffalo to Florence?

You can save a lot of money on your trip from Buffalo to Florence by choosing to travel by bus. The lowest tickets for this trip cost as little as $175.

How much does a bus ticket from Buffalo to Florence cost?

The average price of a one-way ticket from Buffalo to Florence is $269. Over the last 30 days, the prices ranged between $175 and $299, so make sure to compare them to get the best option.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Galleria dell’Accademia, Leonardo Da Vinci Museum, Villa Gamberaia, Museo Galileo - Institute and Museum of the History of Science and Cattedrale Santa Maria del Fiore.

Can I take an overnight bus from Buffalo to Florence?

Yes, you can take a night bus to go from Buffalo to Florence. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.

Buffalo (NY) to Florence (SC), US Bus Tickets

Compare 2 ways to go from Buffalo to Florence.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$175 - $299	Average Duration1d 5h	CO₂ emissions 24kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$269 - $463	Average Duration22h 25m	CO₂ emissions 88kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Buffalo to Florence

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 22 hours 25 minutes and with fares starting at just $269, it presents an excellent value for a comfortable ride.

2train per day

22h 25mAverage Duration

$269Cheapest ticket

88kgCO₂ emissions

Bus Buffalo to Florence: Trip Overview

Average ticket price$269

Average bus trip duration1d 5h

Number of daily buses3

Earliest bus departure7:50am

Distance606 miles (976 km)

Latest bus departure11:59pm

Compare bus companies

FlixBus

3.5/58,487 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/586,956 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Los Limousines, Tornado Bus, Valley Transit, New York Trailways, Wanda Coach

Buffalo to Florence Bus

Busbud helps you find a bus from Buffalo to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Buffalo to Florence will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Buffalo to Florence, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in Buffalo and Florence?

Stops in Buffalo

A - Buffalo Airport

B - Transportation Center

C - Exchange Street Station

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions for your trip Buffalo - Florence

How do I get from Buffalo to Florence without flying?
How long is the bus trip from Buffalo to Florence?
How far is Buffalo from Florence?
What are the departure and arrival stations when taking the bus from Buffalo to Florence?
What is the cheapest way to go from Buffalo to Florence?
How much does a bus ticket from Buffalo to Florence cost?
What are the best sights and things to do in Florence?
Can I take an overnight bus from Buffalo to Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/01

$158

05/02

No data

Today

No data

05/04

No data

05/05

No data

05/06

No data

05/07

No data

05/08

No data

The cheapest trip from Buffalo to Florence was searched and found on May 1, 2025 with a price of $158

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo to Florence, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Buffalo and Florence!

Much more than a mere vehicle taking you from Buffalo to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Buffalo to Florence that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Buffalo to Florence, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Buffalo to Florence?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d 5h	Avg Price$269	Daily Departures3
Vehicle TypeTrain	Travel Time22h 25m	Avg Price$398	Daily Departures2

Will you be returning to Buffalo by bus?

Bus from Buffalo to Florence

You can also go to Florence by train

Train from Buffalo to Florence

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Buffalo, NY to Florence, SC

Compare 2 ways to go from Buffalo to Florence.

Bus Buffalo to Florence: Trip Overview

Compare bus companies

Buffalo to Florence Bus

Where are the popular stops in Buffalo and Florence?

Frequently asked questions for your trip Buffalo - Florence

How do I get from Buffalo to Florence without flying?

How long is the bus trip from Buffalo to Florence?

How far is Buffalo from Florence?

What are the departure and arrival stations when taking the bus from Buffalo to Florence?

What is the cheapest way to go from Buffalo to Florence?

How much does a bus ticket from Buffalo to Florence cost?

What are the best sights and things to do in Florence?

Can I take an overnight bus from Buffalo to Florence?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Buffalo to Florence?

Will you be returning to Buffalo by bus?

You can also go to Florence by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Buffalo

Buses Leaving from Buffalo

Buses Going to Buffalo

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular routes in this country

Popular airport transfers