Train from Boston, MA, US to Florence, SC, US: Tickets & Timetables

Next train departures

Next departures from Boston to Florence on 19 March
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
South Station (Train Terminal)
Florence StationCheapest
AmtrakTrain
Boston Route 128, MA
Florence StationFastest
AmtrakTrain
South Station (Train Terminal)
Florence StationNo tags
Amtrak Acela + Amtrak
Train
South Station (Train Terminal)
Florence StationNo tags
AmtrakTrain
South Station (Train Terminal)
Florence StationNo tags

Last refresh of the prices: Today at 08:20 EDT.

Compare 2 ways to travel from Boston to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 15 minutes and with fares starting at just £71, it presents an excellent value for a comfortable ride.

6bus per day
1d 4hAverage duration
731 milesDistance
29kgCO₂ emissions
Average price£71 - £214Average duration1d 4h
29kg CO₂e
Average price£107 - £780Average duration18h
108kg CO₂e

Frequently asked questions about travelling from Boston, MA, US to Florence, SC, US by train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much does a train ticket cost from Boston to Florence?

    The cheapest train tickets from Boston to Florence start from £107. The average price for this train route is around £220. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the train journey from Boston to Florence?

    The average train journey time from Boston to Florence is 18h, covering a distance of 733 miles. The fastest train gets you there in 17h 15m and is operated by Amtrak.

  3. Which train operators serve the Boston to Florence route?

    Several major train operators run on this route with 8 trains available per day.

  4. What are the earliest and latest departure times for the train from Boston to Florence?

    The earliest train from Boston to Florence departs at 08:12. And the latest train departs at 19:01.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
16/03
No data
17/03
No data
Today
£212
19/03
£276
20/03
No data
21/03
No data
22/03
No data
23/03
No data
busbud logoThe cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on 18 Mar 2026 with a price of £212

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Florence, SC, US as early as possible.

You can expect to pay from £212 to £541 for a train ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £276, which is on 2026-03-19.

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