Train from Boston, MA, US to Florence, SC, US: Tickets & Schedules

Previously seen trips

Next departures for Boston to Florence on December 15
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Back Bay Station
Florence StationNo tags
AmtrakTrain
Boston Route 128, MA
Florence StationNo tags
AmtrakTrain
South Station
Florence StationNo tags
AmtrakTrain
Back Bay Station
Florence StationNo tags
AmtrakTrain
Boston Route 128, MA
Florence StationNo tags

Compare 2 ways to go from Boston to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 15 minutes, and with fares starting at just $121, it presents an excellent value for a comfortable ride.

6bus per day
1d 4hAverage Duration
1179 kmDistance
29kgCO₂ emissions
Average Price$121 - $458Average Duration1d 4h
29kg CO₂e
Average Price$170 - $1,149Average Duration18h
107kg CO₂e

Frequently asked questions about travelling from Boston, MA, US to Florence, SC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Boston to Florence?

    The cheapest train tickets from Boston to Florence start at $170. The average price for this train route is around $560. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

  2. How long is the train ride from Boston to Florence?

    The average train trip from Boston to Florence takes 18h and covers 1180 km. The quickest train gets you there in 17h 15m and is operated by Amtrak.

  3. Which train operators serve the Boston to Florence route?

    Several major train operators serve this route, with 10 trains available per day.

  4. What are the earliest and latest departure times for the train from Boston to Florence?

    The earliest train from Boston to Florence departs at 8:12am. The latest train departs at 7:01pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-13
$507
12-14
$293
Today
No data
12-16
No data
12-17
No data
12-18
No data
12-19
$435
12-20
$597
busbud logoThe cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Dec 14, 2025 with a price of $293

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Florence, SC, US, as early as possible.

You can expect to pay from $293 to $1,093 for a train ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $435 which is on 2025-12-19.

People from around the world trust Busbud