Train from Boston, MA, US to Florence, SC, US: Tickets & Schedules

Next train departures

Next departures for Boston to Florence on January 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
South Station (Train Terminal)
Florence StationCheapest
AmtrakTrain
Boston Route 128, MA
Florence StationFastest
Amtrak Acela + Amtrak
Train
South Station (Train Terminal)
Florence StationNo tags
AmtrakTrain
South Station (Train Terminal)
Florence StationNo tags
Amtrak Acela + Amtrak
Train
South Station (Train Terminal)
Florence StationNo tags

Last refresh of the prices: Yesterday at 2:06 PM EST.

Compare 2 ways to go from Boston to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 15 minutes, and with fares starting at just $136, it presents an excellent value for a comfortable ride.

5bus per day
1d 4hAverage Duration
1183 kmDistance
30kgCO₂ emissions
Average Price$136 - $360Average Duration1d 4h
30kg CO₂e
Average Price$250 - $869Average Duration18h
108kg CO₂e

Frequently asked questions about travelling from Boston, MA, US to Florence, SC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Boston to Florence?

    The cheapest train tickets from Boston to Florence start at $250. The average price for this train route is around $444. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

  2. How long is the train ride from Boston to Florence?

    The average train trip from Boston to Florence takes 18h and covers 1182 km. The quickest train gets you there in 17h 15m and is operated by Amtrak.

  3. Which train operators serve the Boston to Florence route?

    Several major train operators serve this route, with 10 trains available per day.

  4. What are the earliest and latest departure times for the train from Boston to Florence?

    The earliest train from Boston to Florence departs at 8:12am. The latest train departs at 7:01pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01-27
$269
01-28
$318
Today
$300
01-30
No data
01-31
No data
02-01
No data
02-02
No data
02-03
$160
busbud logoThe cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Feb 3, 2026 with a price of $160

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Florence, SC, US, as early as possible.

You can expect to pay from $160 to $975 for a train ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $160 which is on 2026-02-03.

People from around the world trust Busbud