Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Brussels Airport | Santander (Estacion de Autobuses) | Cheapest | ||||
| Bus | Brussels South (Gare du Midi) | Santander (Estacion de Autobuses) | Fastest | ||||
| Bus | Brussels North Train Station | Santander (Estacion de Autobuses) | No tags |
Last refresh of the prices: Last Monday at 18:29 CET.
Get from Brussels to Santander
The journey takes about 20 hours 20 minutes, and with fares starting at just €63, it presents an excellent value for a comfortable ride.
Where are the popular stops in Brussels and Santander?
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- B
Santander Airport
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Compare bus companies
Based on 12160 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at €63
Frequently asked questions about travelling by bus from Brussels to Santander
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Brussels to Santander?
The cheapest coach tickets from Brussels to Santander start from €63. The average price for this route is around €68. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Brussels to Santander?
The average bus journey time from Brussels to Santander is 20h 20m, covering a distance of 1028 km. The fastest bus can take you there in 18h 10m and is operated by FlixBus.
Which bus companies service the Brussels to Santander route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Brussels to Santander?
The earliest bus departs from Brussels to Santander at 10:45. And the latest bus departs at 15:10.
What are the CO₂ emissions for the bus trip from Brussels to Santander?
A bus journey from Brussels to Santander produces an estimated 26 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Santander was searched and found on 30 Jan 2026 with a price of €60To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Santander as early as possible.
You can expect to pay from €60 to €67 for a bus ticket from Brussels to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at €60, which is on 2026-01-30.
