Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Brussels South (Gare du Midi) | Santander (Estacion de Autobuses) | CheapestFastest |
Last refresh of the prices: Yesterday at 4:20 PM CEST.
Get from Brussels to Santander
The journey takes about 21 hours 20 minutes and with fares starting at just NOK 970, it presents an excellent value for a comfortable ride.
Where are the popular stops in Brussels and Santander?
Stops in Brussels
- A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium - B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium - C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Stops in Santander
- A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain - C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Brussels to Santander by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brussels to Santander?
The cheapest bus tickets from Brussels to Santander start from NOK 970. The average price for this route is around NOK 1,691. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Santander?
The average bus trip duration from Brussels to Santander is 21h 20m, covering a distance of 638 miles (1029 km). The quickest bus can get you there in 17h 40m and is operated by FlixBus.
Which bus companies service the Brussels to Santander route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Brussels to Santander?
The earliest bus departs from Brussels to Santander at 9:45am. And the latest bus departs at 3:40pm.
What are the CO₂ emissions for the bus trip from Brussels to Santander?
A bus trip from Brussels to Santander generates an estimated 25.724324999999997 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Santander was searched and found on Jul 7, 2026 with a price of NOK 1,559To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Santander, as early as possible.
