Bus Tickets from Brussels to Santander

Find affordable bus tickets from Brussels to Santander with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 18
from $94
TomorrowMay 19
from $149
TueMay 20
WedMay 21
from $61
ThuMay 22
FriMay 23
SatMay 24
SunMay 25

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 19 at
    Departure city: Brussels
    Departure location: Brussels-North (Gare du Nord)
    Arrival time: May 20 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 19 at
    Departure city: Brussels
    Departure location: Brussels South (Gare du Midi)
    Arrival time: May 20 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Brussels
    Departure location: Brussels Airport
    Arrival time: May 20 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Brussels
    Departure location: Brussels South (Gare du Midi)
    Arrival time: May 20 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Brussels to Santander: Trip Overview

Average ticket price$140
Average bus trip duration19h 25m
Number of daily buses3
Earliest bus departure11:20am
Distance643 miles (1036 km)
Latest bus departure3:10pm

Brussels to Santander Bus

With Busbud, comparing and booking tickets for a bus from Brussels to Santander is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Brussels to Santander from the most reliable bus companies operating this trip.

Discover how much the bus trip from Brussels to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Brussels - Santander

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/16
No data
05/17
No data
Today
$94
05/19
$149
05/20
No data
05/21
$61
05/22
No data
05/23
No data
busbud logoThe cheapest trip from Brussels to Santander was searched and found on May 21, 2025 with a price of $61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Santander, as early as possible.

You can expect to pay from $61 to $159 for a bus ticket from Brussels to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-05-21.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Brussels to Santander.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Brussels to Santander, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Brussels to Santander will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Brussels to Santander, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Brussels by bus?

Bus from Brussels to Santander

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Brussels

Buses Leaving from Brussels

Buses Going to Brussels

Popular Buses Connecting Santander

Buses Leaving from Santander

Buses Going to Santander