Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florence, SC | Jacksonville Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Jacksonville Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Jacksonville Bus Station | No tags |
Last refresh of the prices: Yesterday at 13:40 EDT.
Compare 2 ways to travel from Florence to Jacksonville
Among the sustainable travel choices, the Train stands out as a good way to reach Jacksonville. The journey takes about 6 hours 6 minutes and with fares starting at just CA$93, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Jacksonville
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Frequently asked questions about travelling by bus from Florence, SC, US to Jacksonville, FL
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Florence to Jacksonville?
The cheapest coach tickets from Florence to Jacksonville start from CA$68. The average price for this route is around CA$137. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Florence to Jacksonville?
The average bus journey time from Florence to Jacksonville is 16h 5m, covering a distance of 466 km. The fastest bus can take you there in 5h 45m and is operated by FlixBus.
Which bus companies service the Florence to Jacksonville route?
What is the earliest and latest departure time for the bus from Florence to Jacksonville?
The earliest bus departs from Florence to Jacksonville at 05:45. And the latest bus departs at 16:10.
What are the CO₂ emissions for the bus trip from Florence to Jacksonville?
A bus journey from Florence to Jacksonville produces an estimated 11.62775 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Florence to Jacksonville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15116 reviews.
Which company has the best Wi-Fi from Florence to Jacksonville?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Jacksonville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Jacksonville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Jacksonville, FL was searched and found on 28 Aug 2026 with a price of CA$63To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Jacksonville, FL as early as possible.
You can expect to pay from CA$63 to CA$87 for a bus ticket from Florence, SC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at CA$63, which is on 2026-08-28.
