Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Terminal Bus Palermo | Rome Tiburtina Bus Station | Cheapest | ||||
 | Bus | Terminal Bus Palermo | Tiburtina | Fastest | ||||
| Bus
| Terminal Bus Palermo | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus
| Terminal Bus Palermo | Rome Fiumicino Airport | No tags | ||||
| Bus
| Terminal Bus Palermo | Rome Fiumicino Airport | No tags | ||||
| Bus
| Terminal Bus Palermo | Rome Tiburtina Bus Station | No tags | ||||
| Bus
| Terminal Bus Palermo | Rome Tiburtina Bus Station | No tags | ||||
| Bus
| Terminal Bus Palermo | Rome Anagnina | No tags |
Last refresh of the prices: Today at 17:03 CEST.
Compare 2 ways to travel from Palermo to Rome
Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 11 hours 29 minutes and with fares starting at just €45, it presents an excellent value for a comfortable ride.
Bus stations and stops in Palermo and Rome
Stops in Palermo
- A
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy - B
Palermo Airport
Punta Raisi, 90145, Palermo - C
Piazza Cairoli
Piazza Cairoli, 8-14, 90123 Palermo, Italy - D
Fiera
90143 Palermo PA, Italy - E
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy - F
Piazza Ruggero Settimo, 12
Piazza Ruggero Settimo, 12C, 90139 Palermo, Italy
Stops in Rome
- A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
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Frequently asked questions about travelling by bus from Palermo to Rome
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Palermo to Rome?
The cheapest coach tickets from Palermo to Rome start from €15. The average price for this route is around €53. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Palermo to Rome?
The average bus journey time from Palermo to Rome is 16h 30m, covering a distance of 425 km. The fastest bus can take you there in 12h 15m and is operated by Autoservizi Salemi.
Which bus companies service the Palermo to Rome route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, Autoservizi Salemi, Itabus.
What is the earliest and latest departure time for the bus from Palermo to Rome?
The earliest bus departs from Palermo to Rome at 11:05. And the latest bus departs at 21:10.
What are the CO₂ emissions for the bus trip from Palermo to Rome?
A bus journey from Palermo to Rome produces an estimated 10.609050000000002 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Palermo to Rome?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 573 reviews.
Which company has the best Wi-Fi from Palermo to Rome?
Based on Busbud reviews, the bus company Autoservizi Salemi has the best Wi-Fi rating with a score of 3.9.
Which bus company offers the most punctual service from Palermo to Rome?
According to Busbud traveller reviews, the most punctual bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Palermo to Rome?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Rome was searched and found on 21 Oct 2026 with a price of €41To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Rome as early as possible.
You can expect to pay from €41 to €122 for a bus ticket from Palermo to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at €41, which is on 2026-10-21.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Palermo to Rome?
The Bus is the cheapest travel choice for this destination
