Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Fermata dell'autobus Pisa | Rome Tiburtina Bus Station | Cheapest | |||||
 | Piazza della Stazione, 10 | Tiburtina | Fastest | |||||
| Piazza della Stazione, 10 | Termini | No tags | |||||
 | park Aurelia | Rome Tiburtina Bus Station | No tags | |||||
| Piazza della Stazione, 10 | Termini | No tags |
Last refresh of the prices: Yesterday at 20:48 CEST.
Compare 2 ways to travel from Pisa to Rome
Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 3 hours 45 minutes and with fares starting at just US$23, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Rome?
Stops in Pisa
- APiazza della Stazione, 10, 56125 Pisa PI, Italy
- CVia Pietrasantina, 56123 Pisa PI
- D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy - E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy - F
San Rossore
56122 Pisa PI, Italy
Stops in Rome
- ARoma Trastevere Railway Station, 00152 Roma RM, Italy
- BPiazza dei Cinquecento 1, 00185 Roma RM, Italy
- CLargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - ERoma S.Pietro, 00165 Roma RM, Italy
- FCesano Di Roma, 00123 Roma RM, Italy
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Frequently asked questions about travelling from Pisa to Rome by bus or train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is a ticket from Pisa to Rome?
The cheapest tickets from Pisa to Rome start at US$15. The average price for this route is around US$31. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Pisa to Rome?
The average journey time from Pisa to Rome is 4h 47m, covering a distance of 267 km. The fastest vehicle can get you there in 2h 9m and is operated by Trenitalia.
Which companies operate the Pisa to Rome route?
Several major companies operate on this route with 11 departures available per day, including services from FlixBus, BusItalia, MarinoBus, Itabus, Trenitalia.
What are the earliest and latest departure times from Pisa to Rome?
The earliest trip from Pisa to Rome departs at 00:25. The latest trip departs at 23:30.
What are the CO₂ emissions for the journey from Pisa to Rome?
A journey from Pisa to Rome emits an estimated 6.667462500000001 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Which is the best company from Pisa to Rome?
According to Busbud customers, the highest-rated company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 919 reviews.
Which company has the best Wi-Fi from Pisa to Rome?
According to reviews on Busbud, BusItalia has the best Wi-Fi rating with a score of 3.8.
Which company has the most punctual service from Pisa to Rome?
According to Busbud traveller reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Rome?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Rome was searched and found on 4 May 2026 with a price of US$15To save money and make sure you get the best seat, it's a good idea to buy your bus and train tickets from Pisa to Rome, as early as possible.
You can expect to pay between US$15 and US$200 for a bus or train ticket from Pisa to Rome over the last 2 days. You can expect to find the lowest price for the trip at US$15 on 2026-05-04.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Pisa to Rome?
The Bus is the cheapest travel choice for this destination
