Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Fermata dell'autobus Pisa | Rome Tiburtina Bus Station | Cheapest | |||||
 | Piazza della Stazione, 10 | Tiburtina | Fastest | |||||
| Piazza della Stazione, 10 | Termini | No tags | |||||
 | park Aurelia | Rome Tiburtina Bus Station | No tags | |||||
| Piazza della Stazione, 10 | Termini | No tags |
Last refresh of the prices: Today at 10:01 PM CEST.
Compare 2 ways to go from Pisa to Rome
Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 3 hours 52 minutes and with fares starting at just $23, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Rome?
Stops in Pisa
- A
Piazza della Stazione, 10
Piazza della Stazione, 10, 56125 Pisa PI, Italy - C
Parcheggio Via Pietransantina
Via Pietrasantina, 56123 Pisa PI - D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy - E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy - F
San Rossore
56122 Pisa PI, Italy
Stops in Rome
- A
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy - B
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy - C
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - E
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
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Frequently asked questions about traveling from Pisa to Rome by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Pisa to Rome?
The cheapest tickets from Pisa to Rome start from $18. The average price for this route is around $32. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Pisa to Rome?
The average trip duration from Pisa to Rome is 4h 51m, covering a distance of 166 miles (267 km). The quickest vehicle can get you there in 2h 9m and is operated by Trenitalia.
Which companies service the Pisa to Rome route?
Several major companies operate on this route with 11 trips available per day, including services from FlixBus, BusItalia, MarinoBus, Itabus, Trenitalia.
What is the earliest and latest departure time from Pisa to Rome?
The earliest trip departs from Pisa to Rome at 12:25am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Pisa to Rome?
A trip from Pisa to Rome generates an estimated 6.66525 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Pisa to Rome?
According to Busbud customers, the highest-rated company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 928 reviews.
Which company has the best Wi-Fi from Pisa to Rome?
Based on reviews on Busbud, the company BusItalia has the best Wi-Fi rating with a score of 3.8.
Which company has the most timely service from Pisa to Rome?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Rome?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Rome was searched and found on Jun 11, 2026 with a price of $17To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Rome, as early as possible.
You can expect to pay from $17 to $145 for a bus or train ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2026-06-11.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Pisa to Rome?
The Bus is the cheapest travel choice for this destination
