Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | PRG Airport | Rome Tiburtina Bus Station | Cheapest | ||||
| Bus | Prague (Main Station - parking) | Rome Tiburtina Bus Station | Fastest | ||||
| Bus | Prague (Central Bus Station Florenc) | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Prague (Main Station - parking) | Aeroporto Ciampino Airport (CIA) | No tags |
Last refresh of the prices: Yesterday at 07:34 CET.
Compare 2 ways to travel from Prague to Rome
Among the sustainable travel choices, the Carpool stands out as a good way to reach Rome. The journey takes about 13 hours 20 minutes and with fares starting at just £52, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£39 - £227 | Average duration1d | 23kg CO₂e | ||
Carpool | Average price£52 - £52 | Average duration13h 20m | 39kg CO₂e |
Where are the popular stops in Prague and Rome?
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CAviatická, 161 08, Praha 6, Czechia
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
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Frequently asked questions about travelling by bus from Prague to Rome
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Prague to Rome?
The cheapest coach tickets from Prague to Rome start from £39. The average price for this route is around £88. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Prague to Rome?
The average bus journey time from Prague to Rome is 1d , covering a distance of 579 miles. The fastest bus can take you there in 19h 15m and is operated by FlixBus.
Which bus companies service the Prague to Rome route?
Several major bus companies operate on this route with 45 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Prague to Rome?
The earliest bus departs from Prague to Rome at 02:30. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Prague to Rome?
A bus journey from Prague to Rome produces an estimated 23 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Prague to Rome?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1066 reviews.
Which company has the best Wi-Fi from Prague to Rome?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Prague to Rome?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Prague to Rome?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Rome was searched and found on 26 Jan 2026 with a price of £43To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome as early as possible.
You can expect to pay from £43 to £114 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at £43, which is on 2026-01-26.
