Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florenc | Rome Tiburtina Bus Station | Cheapest | ||||
 | Bus | Prague (Na Knížecí) | Rome Tiburtina Bus Station | Fastest | ||||
| Bus | Prague (Central Bus Station Florenc) | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Prague (Main Station - parking) | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Prague (Main Station - parking) | Aeroporto Ciampino Airport (CIA) | No tags |
Last refresh of the prices: Yesterday at 11:46 PM CET.
Get from Prague to Rome
The journey takes about 1 day, 30 minutes, and with fares starting at just $71, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Rome?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DChlumecká, 198 00 Praha 20, Czech Republic
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
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Frequently asked questions about travelling from Prague to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Rome?
The cheapest bus tickets from Prague to Rome start from $71. The average price for this route is around $163. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Rome?
The average bus travel time from Prague to Rome is 1d , covering a distance of 928 km. The quickest bus can get you there in 19h 15m and is operated by FlixBus.
Which bus companies service the Prague to Rome route?
Several major bus companies operate on this route with 51 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Prague to Rome?
The earliest bus departs from Prague to Rome at 2:30am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Prague to Rome?
A bus trip from Prague to Rome generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Prague to Rome?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1069 reviews.
Which bus company has the best Wi-Fi from Prague to Rome?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Prague to Rome?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Rome?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Rome was searched and found on Mar 30, 2026 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.
You can expect to pay from $121 to $415 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2026-03-30.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
