Bus Tickets from Prague to Rome

Find affordable bus tickets from Prague to Rome with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 12
from $64
TomorrowMay 13
from $94
WedMay 14
from $86
ThuMay 15
from $82
FriMay 16
from $64
SatMay 17
from $78
SunMay 18
from $77
MonMay 19
from $57

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 13 at
    Departure city: Prague
    Departure location: PRG Airport
    Arrival time: May 14 at
    Destination city: Rome
    Destination location: Rome Anagnina
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 13 at
    Departure city: Prague
    Departure location: Prague (Na Knížecí)
    Arrival time: May 14 at
    Destination city: Rome
    Destination location: Rome Tiburtina Bus Station
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 13 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: May 14 at
    Destination city: Rome
    Destination location: Rome Fiumicino Airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 13 at
    Departure city: Prague
    Departure location: Prague (Main Station - parking)
    Arrival time: May 14 at
    Destination city: Rome
    Destination location: Rome Fiumicino Airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 13 at
    Departure city: Prague
    Departure location: Prague (Na Knížecí)
    Arrival time: May 14 at
    Destination city: Rome
    Destination location: Rome Fiumicino Airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Prague to Rome.

Average Price$50 - $303Average Duration1d
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$122 - $122Average Duration15h 40m
39kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Prague to Rome

Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 15 hours 40 minutes and with fares starting at just $122, it presents an excellent value for a comfortable ride.

1carpool per day
15h 40mAverage Duration
$122Cheapest ticket
39kgCO₂ emissions

Bus Prague to Rome: Trip Overview

Average ticket price$120
Average bus trip duration1d
Number of daily buses44
Earliest bus departure2:30am
Distance580 miles (935 km)
Latest bus departure11:50pm

Prague to Rome Bus

Busbud helps you find a bus from Prague to Rome. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Prague to Rome.

Whether it is cheap bus tickets or more luxurious buses going to Rome from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Prague - Rome

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/10
$107
05/11
$107
Today
$65
05/13
$94
05/14
$86
05/15
$82
05/16
$65
05/17
$78
busbud logoThe cheapest trip from Prague to Rome was searched and found on May 16, 2025 with a price of $65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.

You can expect to pay from $65 to $193 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $65 which is on 2025-05-16.

Usually Flixbus (CZ) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Prague and Rome!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Prague to Rome.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Rome.

Tune out to the fine sounds of your best music playlist on your bus trip from Prague to Rome while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Prague to Rome?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Prague by bus?

Bus from Prague to Rome

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Prague

Buses Leaving from Prague

Buses Going to Prague

Popular Buses Connecting Rome

Buses Leaving from Rome

Buses Going to Rome