What is the distance between Prague and Rome?

Prague and Rome are 573 miles (925 km) apart.

What are the departure and arrival stations when taking the bus from Prague to Rome?

If you're headed to Rome from Prague, chances are that your bus will depart from PRG Airport and arrive at Rome Tiburtina Bus Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Rome?

Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are Colosseum, Piazza Navona, Cooking Classes and Food Tours in Rome, Pantheon and Teatro dell'Opera di Roma.

Bus Prague to Rome from $58 | Refundable Tickets

Next bus departures

Next departures for Prague to Rome on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:50pm	PRG Airport	22h 35m	5:25pm	Rome Tiburtina Bus Station	Cheapest
Bus	2:15pm	Prague (Main Station - parking)	19h 15m	9:30am	Rome Tiburtina Bus Station	Fastest
Bus	9:25pm	Prague (Central Bus Station Florenc)	21h	6:25pm	Aeroporto Ciampino Airport (CIA)	No tags
Bus	11:45pm	Prague (Central Bus Station Florenc)	1d 4h	4:35am	Aeroporto Ciampino Airport (CIA)	No tags
Bus	8:20pm	Prague (Main Station - parking)	22h 5m	6:25pm	Aeroporto Ciampino Airport (CIA)	No tags

Last refresh of the prices: Yesterday at 12:48 PM CET.

Get from Prague to Rome

This route is served by bus only

The journey takes about 1 day, 20 minutes and with fares starting at just $50, it presents an excellent value for a comfortable ride.

46bus per day

1d Average Duration

581 milesDistance

23kgCO₂ emissions

Where are the popular stops in Prague and Rome?

Stops in Prague

A
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
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B
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
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C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
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E
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
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F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
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Stops in Rome

A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
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B
Rome Ciampino Airport
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C
Rome Fiumicino Airport
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D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Compare bus companies

FlixBus

3.5/511,407 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

RegioJet

4/51,057 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wifi3.8

BlaBlaCar Bus

3.5/511,148 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Prague to Rome by bus

What is the distance between Prague and Rome?
What are the departure and arrival stations when taking the bus from Prague to Rome?
What are the best sights and things to do in Rome?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

$82

11/22

$63

Today

$88

11/24

$67

11/25

No data

11/26

No data

11/27

$67

11/28

No data

The cheapest trip from Prague to Rome was searched and found on Nov 22, 2025 with a price of $63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.

You can expect to pay from $63 to $241 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-11-27.