Bus Tickets from Prague to Rome

Next bus departures

Next departures for Prague to Rome on November 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixbusBus
PRG Airport
Rome Tiburtina Bus StationCheapest
FlixbusBus
Prague (Main Station - parking)
Rome Tiburtina Bus StationFastest
FlixbusBus
Prague (Central Bus Station Florenc)
Aeroporto Ciampino Airport (CIA)No tags
FlixbusBus
Prague (Central Bus Station Florenc)
Aeroporto Ciampino Airport (CIA)No tags
FlixbusBus
Prague (Main Station - parking)
Aeroporto Ciampino Airport (CIA)No tags

Last refresh of the prices: Yesterday at 12:48 PM CET.

Get from Prague to Rome

This route is served by bus only

The journey takes about 1 day, 20 minutes and with fares starting at just $50, it presents an excellent value for a comfortable ride.

46bus per day
1d Average Duration
581 milesDistance
23kgCO₂ emissions

Frequently asked questions about traveling from Prague to Rome by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/21
$82
11/22
$63
Today
$88
11/24
$67
11/25
No data
11/26
No data
11/27
$67
11/28
No data
busbud logoThe cheapest trip from Prague to Rome was searched and found on Nov 22, 2025 with a price of $63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.

You can expect to pay from $63 to $241 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-11-27.

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