Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Big Pine Key, FL | Boston (South Station) | CheapestFastest | ||||
 | Bus | Big Pine Key, FL | Boston (South Station) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Big Pine Key, FL | Brookline | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Big Pine Key, FL | Brookline | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Big Pine Key, FL | 151 Steel Pl, Cambridge | No tags |
Last refresh of the prices: Today at 7:46 AM EST.
Get from Big Pine Key to Boston
The journey takes about 1 day, 19 hours, and with fares starting at just R 3 883, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87434 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 3 883
Frequently asked questions about travelling from Big Pine Key to Boston, MA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Big Pine Key to Boston?
The cheapest bus tickets from Big Pine Key to Boston start at R 3 883. The average price for this route is around R 4 347. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Big Pine Key to Boston?
The average bus journey time from Big Pine Key to Boston is 1d 19h, covering a distance of 2179 km. The fastest bus gets you there in 1d 18h and is operated by Greyhound.
Which bus companies service the Big Pine Key to Boston route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Big Pine Key to Boston?
The earliest bus departs from Big Pine Key to Boston at 10:40. And the latest bus departs at 17:40.
What are the CO₂ emissions for the bus trip from Big Pine Key to Boston?
A bus trip from Big Pine Key to Boston produces an estimated 54 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Big Pine Key to Boston, MA, US was searched and found on 17 Dec 2025 with a price of R 3 880To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Big Pine Key to Boston, MA, US as early as possible.
You can expect to pay from R 3 880 to R 3 880 for a bus ticket from Big Pine Key to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 880, which is on 2025-12-17.
