Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Boston (South Station) | Winston Salem Greyhound Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | Winston Salem Greyhound Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Boston (South Station) | Winston Salem Greyhound Bus Station | No tags | ||||
 | Bus | Boston (South Station) | Winston Salem Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 151 Steel Pl, Cambridge | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Last Sunday at 2:24 AM EST.
Get from Boston to Winston-Salem
The journey takes about 21 hours 45 minutes, and with fares starting at just R 1 587, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Winston-Salem?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about travelling from Boston, MA, US to Winston-Salem by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Boston to Winston-Salem?
The cheapest bus tickets from Boston to Winston-Salem start at R 1 587. The average price for this route is around R 2 134. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Boston to Winston-Salem?
The average bus journey time from Boston to Winston-Salem is 21h 45m, covering a distance of 1053 km. The fastest bus gets you there in 17h 35m and is operated by FlixBus.
Which bus companies service the Boston to Winston-Salem route?
What is the earliest and latest departure time for the bus from Boston to Winston-Salem?
The earliest bus departs from Boston to Winston-Salem at 08:55. And the latest bus departs at 21:50.
What are the CO₂ emissions for the bus trip from Boston to Winston-Salem?
A bus trip from Boston to Winston-Salem produces an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Boston to Winston-Salem?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Boston to Winston-Salem?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Boston to Winston-Salem?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Winston-Salem?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Winston-Salem was searched and found on 25 Jan 2026 with a price of R 1 601To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Winston-Salem as early as possible.
You can expect to pay from R 1 601 to R 2 115 for a bus ticket from Boston, MA, US to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 601, which is on 2026-01-25.
