Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Brussels-South (Gare du Midi) | Estación Sur | Cheapest | |||||
| Brussels-South (Gare du Midi) | Aeropuerto Madrid - Barajas T4 (E) | Fastest | |||||
| Brussels-South (Gare du Midi) | Estación Sur | No tags | |||||
 | Brussels Airport | Madrid (South) | No tags | |||||
| Brussels Airport | Madrid (South) | No tags |
Last refresh of the prices: Today at 1:34 PM CET.
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Compare 2 ways to travel from Brussels to Madrid
Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 16 hours 30 minutes and with fares starting at just US$121, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | ||
|---|---|---|---|---|
| Average priceUS$52 - US$353 | Average duration22h 25m | 33kg CO₂e | ||
Carpool | Average priceUS$121 - US$168 | Average duration16h 30m | 55kg CO₂e |
Bus Brussels to Madrid: Trip Overview
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Brussels to Madrid Bus
With Busbud, comparing and booking tickets for a bus from Brussels to Madrid is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Brussels to Madrid will be provided by the most trusted bus companies.
Discover how much the bus trip from Brussels to Madrid will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Brussels and Madrid?
Frequently asked questions on the trip Brussels - Madrid
How much does a bus ticket from Brussels to Madrid cost?
The bus ticket price from Brussels to Madrid starts at US$52. The best way to find cheap bus tickets from Brussels to Madrid is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Brussels to Madrid?
The average travel time between Brussels and Madrid is around 22h 25m, although the fastest bus will take about 20h. This is the time it takes to travel the 1318 km that separates the two cities.
How many daily bus connections are there between Brussels and Madrid?
The number of buses from Brussels to Madrid can differ depending on the day of the week. On average, there are 14 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Brussels to Madrid by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Brussels to Madrid?
When taking the bus from Brussels to Madrid, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Brussels to Madrid?
Buses travelling between Brussels and Madrid leave from Brussels South (Gare du Midi) or Brux-Nord and arrive at Estación Sur, Madrid-Barajas Airport, Avenida de América Metro.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Madrid was searched and found on 05 Nov 2025 with a price of US$52To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Madrid as early as possible.
You can expect to pay from US$52 to US$204 for a bus ticket from Brussels to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at US$52, which is on 2025-11-05.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Brussels to Madrid.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Brussels to Madrid, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Brussels to Madrid will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Brussels to Madrid.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Brussels to Madrid?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Brussels
Buses Leaving from Brussels
- Bus from Brussels to Charleroi
- Coach Brussels - Bruges
- Bus Brussels - London
- Bus from Brussels to Ghent
- Coach Brussels - Barcelona
- Bus Brussels - Amsterdam
- Bus from Brussels to Turnhout
- Coach Brussels - Bastogne
- Bus Brussels - Leuven
- Bus from Brussels to Arlon
- Coach Brussels - Liège
- Bus Brussels - Mons
- Bus from Brussels to Antwerp
- Coach Brussels - Hasselt
- Bus Brussels - Kortrijk
Buses Going to Brussels
- Bus from Charleroi to Brussels
- Coach Amsterdam - Brussels
- Bus Paris - Brussels
- Bus from Berlin to Brussels
- Coach Tours - Brussels
- Bus Lille - Brussels
- Bus from Hasselt to Brussels
- Coach Arlon - Brussels
- Bus Bruges - Brussels
- Bus from Ghent to Brussels
- Coach Bastogne - Brussels
- Bus Leuven - Brussels
- Bus from Kortrijk to Brussels
- Coach Antwerp - Brussels
- Bus Turnhout - Brussels
Popular Buses Connecting Madrid
Buses Leaving from Madrid
- Bus from Madrid to Barcelona
- Coach Madrid - Valencia
- Bus Madrid - Paris
- Bus from Madrid to Bilbao
- Coach Madrid - Málaga
- Bus Madrid - Salamanca
- Bus from Madrid to Perales De Tajuna
- Coach Madrid - Vilalba
- Bus Madrid - Comillas
- Bus from Madrid to Peñalba de San Esteban
- Coach Madrid - Fuentiduena De Tajo
- Bus Madrid - Jabugo
- Bus from Madrid to Quintanar del Rey
- Coach Madrid - El Molinillo
- Bus Madrid - Carrascalejo
Buses Going to Madrid
- Bus from Barcelos to Madrid
- Coach Valencia - Madrid
- Bus El Oso - Madrid
- Bus from Dortmund to Madrid
- Coach Ciudad Real - Madrid
- Bus Girona - Madrid
- Bus from Urda to Madrid
- Coach El Torno - Madrid
- Bus Cilleruelo de Bezana - Madrid
- Bus from Torrijos to Madrid
- Coach Magacela - Madrid
- Bus Villacañas - Madrid
- Bus from Almazán to Madrid
- Coach Santibáñez de Béjar - Madrid
- Bus Castrovega de Valmadrigal - Madrid