Next departures from Brussels to Prague on 4 August
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels South (Gare du Midi)
Prague (Central Bus Station Florenc)
Cheapest
Bus
Brussels South (Gare du Midi)
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 5 August
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels South (Gare du Midi)
Prague (Central Bus Station Florenc)
Cheapest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 6 August
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Train Station
Prague (Main Railway Station)
Cheapest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Station - parking)
No tags
Next departures from Brussels to Prague on 7 August
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Florenc
Cheapest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Florenc
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 8 August
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels South (Gare du Midi)
Prague (Central Bus Station Florenc)
Cheapest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 11 August
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels South (Gare du Midi)
Prague (Central Bus Station Florenc)
Cheapest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Last refresh of the prices: Today at 2:11 PM CEST.
Compare 2 ways to travel from Brussels to Prague
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 18 hours 35 minutes and with fares starting at just ARS 51 163, it presents an excellent value for a comfortable ride.
Based on 14947 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. FlixBus ticket prices on this trip start at ARS 51 163
Based on 12460 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. BlaBlaCar Bus ticket prices on this trip start at ARS 97 426
Based on 1102 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the departure location but often complained about the Wi-Fi. RegioJet ticket prices on this trip start at ARS 67 962
RegioJet Brussels Prague recent customer reviews
RegioJet is the best bus
Every Thing was nice
Very good
Musil Tour offers 1 daily departures, and you can find tickets starting at ARS 131 606. The quickest ride takes around 17 hours 40 minutes. Musil Tour offers a cost-effective solution to get you where you need to be.
Frequently asked questions about travelling from Brussels to Prague by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Brussels to Prague?
The cheapest bus tickets from Brussels to Prague start at ARS 51 163. The average price for this route is around ARS 155 311. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Brussels to Prague?
The average bus journey time from Brussels to Prague is 18h 35m, covering a distance of 713 km. The fastest bus gets you there in 11h 55m and is operated by RegioJet.
Which bus companies service the Brussels to Prague route?
Several major bus companies operate on this route with 51 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet, Musil Tour.
What is the earliest and latest departure time for the bus from Brussels to Prague?
The earliest bus departs from Brussels to Prague at 00:45. And the latest bus departs at 22:55.
What are the CO₂ emissions for the bus trip from Brussels to Prague?
A bus trip from Brussels to Prague produces an estimated 17.811275000000002 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Brussels to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1083 reviews.
Which bus company has the best Wi-Fi from Brussels to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Brussels to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
02/08
ARS 150 227
03/08
ARS 133 673
Today
ARS 133 688
05/08
ARS 124 653
06/08
ARS 124 653
07/08
ARS 113 796
08/08
ARS 124 883
09/08
ARS 107 150
The cheapest trip from Brussels to Prague was searched and found on 09 Aug 2026 with a price of ARS 107 150
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague as early as possible.
You can expect to pay from ARS 107 150 to ARS 332 398 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 107 150, which is on 2026-08-09.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Brussels to Prague was searched and found on 09 Aug 2026 with a price of ARS 107 150
