Previously seen journeys

Next departures from Chicago to Florence on 3 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
Greyhound + FlixBus	Bus	18:40	Chicago 95Th & Dan Ryan	1d 4h	00:05	Florence, SC
Greyhound + FlixBus	Bus	22:00	537-517 W. Jackson Blvd	1d 6h	05:45	Florence, SC
FlixBus + Greyhound	Bus	22:30	Chicago 95Th & Dan Ryan	1d 6h	05:45	Florence, SC
FlixBus + Greyhound	Bus	23:15	Downtown Greyhound Station	1d 5h	05:45	Florence, SC
FlixBus + Greyhound	Bus	22:00	537-517 W. Jackson Blvd	1d 13h	12:45	Bus station

Compare 2 ways to travel from Chicago to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 5 hours 34 minutes and with fares starting at just TRY 4 099, it presents an excellent value for a comfortable ride.

10bus per day

1d 5hAverage duration

1092 kmDistance

27kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceTRY 4 099 - TRY 17 619	Average duration1d 5h	CO₂ emissions 27kg CO₂e
Train	Average priceTRY 13 321 - TRY 23 405	Average duration1d 7h	CO₂ emissions 100kg CO₂e

Bus stations and stops in Chicago and Florence

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/587 794 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

WiFi2.5

FlixBus

3.5/513 945 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

WiFi2.7

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about travelling from Chicago to Florence, SC, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Chicago to Florence?
The cheapest bus tickets from Chicago to Florence start at TRY 4 099. The average price for this route is around TRY 6 974. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Chicago to Florence?
The average bus journey time from Chicago to Florence is 1d 5h, covering a distance of 1092 km. The fastest bus gets you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Chicago to Florence route?
Several major bus companies operate on this route with 10 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Chicago to Florence?
The earliest bus departs from Chicago to Florence at 05:25. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Chicago to Florence?
A bus trip from Chicago to Florence produces an estimated 27.284249999999997 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Chicago to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87588 reviews.
Which bus company has the best Wi-Fi from Chicago to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Chicago to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/08

No data

02/08

No data

Today

No data

04/08

No data

05/08

No data

06/08

TRY 5 577

07/08

No data

08/08

TRY 5 943

The cheapest trip from Chicago to Florence, SC, US was searched and found on 06 Aug 2026 with a price of TRY 5 577

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Florence, SC, US as early as possible.

You can expect to pay from TRY 5 577 to TRY 5 943 for a bus ticket from Chicago to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at TRY 5 577, which is on 2026-08-06.