Bus Tickets from Chicago to Florence, SC, US

Previously seen trips

Next departures for Chicago to Florence on November 20
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
537-517 W. Jackson Blvd
Florence, SCNo tags
FlixBus + Greyhound
Bus
Downtown Greyhound Station
Florence, SCNo tags
Greyhound + FlixBus
Bus
Chicago 95Th & Dan Ryan
Florence, SCNo tags
FlixBus + Greyhound
Bus
Chicago 95Th & Dan Ryan
Florence, SCNo tags
Greyhound + FlixBus
Bus
Downtown Greyhound Station
Florence, SCNo tags

Compare 2 ways to go from Chicago to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 1 day, 4 hours 25 minutes and with fares starting at just $112, it presents an excellent value for a comfortable ride.

11bus per day
1d 4hAverage Duration
672 milesDistance
27kgCO₂ emissions
Average Price$112 - $310Average Duration1d 4h
27kg CO₂e
Average Price$198 - $465Average Duration1d 7h
100kg CO₂e

Frequently asked questions about traveling from Chicago to Florence, SC, US by bus

What's the cheapest way to go from Chicago to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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