How much is the bus ticket from Chicago to Florence?

The cheapest bus tickets from Chicago to Florence start from $159. The average price for this route is around $255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Chicago to Florence?

The average bus travel time from Chicago to Florence is 1d 4h, covering a distance of 1084 km. The quickest bus can get you there in 1d 2h and is operated by Greyhound .

Which bus companies service the Chicago to Florence route?

Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from Chicago to Florence?

The earliest bus departs from Chicago to Florence at 10:00am. And the latest bus departs at 11:50pm.

What are the CO₂ emissions for the bus trip from Chicago to Florence?

A bus trip from Chicago to Florence generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Chicago to Florence?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87500 reviews.

Which bus company has the best Wi-Fi from Chicago to Florence?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Chicago to Florence?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Chicago to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Chicago to Florence from $149 | Refundable Tickets

Previously seen trips

Next departures for Chicago to Florence on January 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	6:00pm	Downtown Greyhound Station	1d 4h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	6:40pm	Chicago 95Th & Dan Ryan	1d 4h	11:59pm	Florence, SC	No tags
FlixBus + Greyhound	Bus	8:05pm	Chicago 95Th & Dan Ryan	1d 8h	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	8:05pm	Chicago 95Th & Dan Ryan	1d 8h	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	8:05pm	Chicago 95Th & Dan Ryan	1d 15h	12:45pm	Bus station	No tags

Compare 2 ways to go from Chicago to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 25 minutes, and with fares starting at just $159, it presents an excellent value for a comfortable ride.

11bus per day

1d 4hAverage Duration

1084 kmDistance

27kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$159 - $444	Average Duration1d 4h	CO₂ emissions 27kg CO₂e
Train	Average Price$408 - $729	Average Duration1d 7h	CO₂ emissions 100kg CO₂e

Where are the popular stops in Chicago and Florence?

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page Map
B
Chicago O'Hare International Airport
Visit page Map
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
Map
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
Map
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
Map
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Map

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page Map
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Map

Compare bus companies

Greyhound

3.5/587,501 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/512,054 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Chicago to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Chicago to Florence?
The cheapest bus tickets from Chicago to Florence start from $159. The average price for this route is around $255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Florence?
The average bus travel time from Chicago to Florence is 1d 4h, covering a distance of 1084 km. The quickest bus can get you there in 1d 2h and is operated by Greyhound.
Which bus companies service the Chicago to Florence route?
Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Chicago to Florence?
The earliest bus departs from Chicago to Florence at 10:00am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Chicago to Florence?
A bus trip from Chicago to Florence generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Chicago to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Chicago to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Chicago to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-13

No data

01-14

$243

Today

No data

01-16

No data

01-17

No data

01-18

$174

01-19

No data

01-20

No data

The cheapest trip from Chicago to Florence, SC, US was searched and found on Jan 18, 2026 with a price of $174

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Florence, SC, US, as early as possible.

You can expect to pay from $174 to $243 for a bus ticket from Chicago to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $174 which is on 2026-01-18.