Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Via Gandhi | Terminal Bus Palermo | Cheapest | ||||
| Bus | Via Gandhi | Palermo Via Oreto | Fastest |
Last refresh of the prices: Today at 11:06 AM CEST.
Get from Comiso to Palermo
The journey takes about 4 hours 50 minutes, and with fares starting at just R 435, it presents an excellent value for a comfortable ride.
Where are the popular stops in Comiso and Palermo?
Stops in Comiso
- A
Fermata dell'autobus Comiso
Viale della Resistenza, 643, 97013 Comiso RG, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Based on 489 reviews, the company was rated 4.3 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. SAIS Autolinee ticket prices on this trip start at R 435
Frequently asked questions about travelling from Comiso to Palermo by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Comiso to Palermo?
The cheapest bus tickets from Comiso to Palermo start at R 435. The average price for this route is around R 438. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Comiso to Palermo?
The average bus journey time from Comiso to Palermo is 4h 50m, covering a distance of 167 km. The fastest bus gets you there in 4h 50m and is operated by SAIS Autolinee.
Which bus companies service the Comiso to Palermo route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Comiso to Palermo?
The earliest bus departs from Comiso to Palermo at 06:40. And the latest bus departs at 06:40.
What are the CO₂ emissions for the bus trip from Comiso to Palermo?
A bus trip from Comiso to Palermo produces an estimated 4.16645 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Comiso to Palermo was searched and found on 04 Apr 2026 with a price of R 392To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Comiso to Palermo as early as possible.
You can expect to pay from R 392 to R 397 for a bus ticket from Comiso to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at R 396, which is on 2026-04-07.
