Find coaches from Des Moines to Milwaukee

Next departures

Next departures from Des Moines to Milwaukee on 1 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Des Moines
Milwaukee Bus Station, St. Paul & N6th road.Cheapest
Greyhound Lines, Inc. + FlixBus
Des Moines
Milwaukee Mitchell MKE AirportFastest
Greyhound Lines, Inc.
Des Moines
Milwaukee Bus Station, St. Paul & N6th road.No tags
Greyhound Lines, Inc. + FlixBus
Des Moines
Goerke's Corners Park & Ride (Brookfield)No tags

Last refresh of the prices: Last Sunday at 7:38 PM CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Get from Des Moines to Milwaukee

busbud logoThis route is served by bus only

The journey takes about 12 hours 5 minutes, and with fares starting at just US$61, it presents an excellent value for a comfortable ride.

4bus per day
12h 5mAverage duration
492 kmDistance
12kgCO₂ emissions

Bus Des Moines to Milwaukee: Trip Overview

Average ticket priceUS$85
Average bus trip duration12h 5m
Number of daily buses4
Earliest bus departure00:01
Distance492 km
Latest bus departure09:30

Des Moines to Milwaukee Bus

Busbud helps you find a bus from Des Moines to Milwaukee. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Milwaukee from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Milwaukee from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Des Moines - Milwaukee

  1. How much does a bus ticket from Des Moines to Milwaukee cost?

    The bus ticket price from Des Moines to Milwaukee starts at US$61. The best way to find cheap bus tickets from Des Moines to Milwaukee is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Des Moines to Milwaukee?

    The average travel time between Des Moines and Milwaukee is around 12h 5m, although the fastest bus will take about 11h 15m. This is the time it takes to travel the 496 km that separates the two cities.

  3. How many daily bus connections are there between Des Moines and Milwaukee?

    The number of buses from Des Moines to Milwaukee can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Des Moines to Milwaukee by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Des Moines to Milwaukee?

    When taking the bus from Des Moines to Milwaukee, you can travel comfortably and safely with Jefferson Lines, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Des Moines to Milwaukee?

    Buses travelling between Des Moines and Milwaukee leave from Jefferson/Trailways Depot or 1514 East Grand Ave and arrive at Milwaukee Airport, Intermodal Station, S Cesar Chavez.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$104
29/10
US$92
Today
US$118
31/10
No data
01/11
US$57
02/11
No data
03/11
No data
04/11
No data
busbud logoThe cheapest trip from Des Moines to Milwaukee was searched and found on 01 Nov 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Milwaukee as early as possible.

You can expect to pay from US$57 to US$118 for a bus ticket from Des Moines to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at US$57, which is on 2025-11-01.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Milwaukee!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Milwaukee, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Milwaukee.

Make a music playlist for your bus ride from Des Moines to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from Milwaukee to Des Moines

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines

Popular Buses Connecting Milwaukee

Buses Leaving from Milwaukee

Buses Going to Milwaukee