Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | 1116 Woodruff Rd | Bus station | CheapestFastest |
Last refresh of the prices: 12/29/2025 EST.
Compare 2 ways to travel from Greenville to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 4 hours 40 minutes and with fares starting at just R 1 204, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Florence?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Based on 11915 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 542
Frequently asked questions about travelling from Greenville, SC to Florence, SC, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Greenville to Florence?
The cheapest bus tickets from Greenville to Florence start at R 1 204. The average price for this route is around R 1 644. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Greenville to Florence?
The average bus journey time from Greenville to Florence is 4h 40m, covering a distance of 244 km. The fastest bus gets you there in 13h 30m and is operated by FlixBus.
Which bus companies service the Greenville to Florence route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Greenville to Florence?
The earliest bus departs from Greenville to Florence at 10:50. And the latest bus departs at 10:50.
What are the CO₂ emissions for the bus trip from Greenville to Florence?
A bus trip from Greenville to Florence produces an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What's the cheapest way to go from Greenville, SC to Florence, SC, US?
The bus is the cheapest travel choice for this destination
