How much is the bus ticket from Harrisburg to St. Louis?

The cheapest bus tickets from Harrisburg to St. Louis start at R 1 434. The average price for this route is around R 2 067. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Harrisburg to St. Louis?

The average bus journey time from Harrisburg to St. Louis is 20h 35m, covering a distance of 1158 km. The fastest bus gets you there in 18h 5m and is operated by Greyhound .

Which bus companies service the Harrisburg to St. Louis route?

Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Harrisburg to St. Louis?

The earliest bus departs from Harrisburg to St. Louis at 02:30. And the latest bus departs at 21:10.

What are the CO₂ emissions for the bus trip from Harrisburg to St. Louis?

A bus trip from Harrisburg to St. Louis produces an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Harrisburg to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87518 reviews.

Which bus company has the best Wi-Fi from Harrisburg to St. Louis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Harrisburg to St. Louis?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Harrisburg to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Harrisburg to St. Louis from R 1 365 | Refundable Tickets

Next bus departures

Next departures from Harrisburg to St. Louis on 7 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	19:45	Harrisburg Bus Station	20h 35m	15:20	Gateway Station	Cheapest
Bus	20:05	Harrisburg Bus Station	20h 15m	15:20	Gateway Station	Fastest
Bus	21:10	Harrisburg Bus Station	1d 3h	23:25	Gateway Station	No tags

Next departures from Harrisburg to St. Louis on 8 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	19:45	Harrisburg Bus Station	20h 35m	15:20	Gateway Station	Cheapest
Bus	14:50	Harrisburg Bus Station	18h 5m	07:55	Gateway Station	Fastest
Bus	02:30	Harrisburg Bus Station	21h 55m	23:25	Gateway Station	No tags
Bus	20:05	Harrisburg Bus Station	20h 15m	15:20	Gateway Station	No tags
Bus	21:10	Harrisburg Bus Station	1d 3h	23:25	Gateway Station	No tags

Next departures from Harrisburg to St. Louis on 9 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	19:45	Harrisburg Bus Station	20h 35m	15:20	Gateway Station	Cheapest
Bus	14:50	Harrisburg Bus Station	18h 5m	07:55	Gateway Station	Fastest
Bus	02:30	Harrisburg Bus Station	21h 55m	23:25	Gateway Station	No tags
Bus	20:05	Harrisburg Bus Station	20h 15m	15:20	Gateway Station	No tags
Bus	21:10	Harrisburg Bus Station	1d 3h	23:25	Gateway Station	No tags

Next departures from Harrisburg to St. Louis on 10 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	14:50	Harrisburg Bus Station	18h 5m	07:55	Gateway Station	CheapestFastest
Bus	02:30	Harrisburg Bus Station	21h 55m	23:25	Gateway Station	No tags
Bus	19:45	Harrisburg Bus Station	20h 35m	15:20	Gateway Station	No tags
Bus	20:05	Harrisburg Bus Station	20h 15m	15:20	Gateway Station	No tags
Bus	21:10	Harrisburg Bus Station	1d 3h	23:25	Gateway Station	No tags

Next departures from Harrisburg to St. Louis on 11 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	19:45	Harrisburg Bus Station	20h 35m	15:20	Gateway Station	Cheapest
Bus	14:50	Harrisburg Bus Station	18h 5m	07:55	Gateway Station	Fastest
Bus	02:30	Harrisburg Bus Station	21h 55m	23:25	Gateway Station	No tags
Bus	20:05	Harrisburg Bus Station	20h 15m	15:20	Gateway Station	No tags
Bus	21:10	Harrisburg Bus Station	1d 3h	23:25	Gateway Station	No tags

Next departures from Harrisburg to St. Louis on 12 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	14:50	Harrisburg Bus Station	18h 5m	07:55	Gateway Station	CheapestFastest
Bus	02:30	Harrisburg Bus Station	21h 55m	23:25	Gateway Station	No tags
Bus	19:45	Harrisburg Bus Station	20h 35m	15:20	Gateway Station	No tags
Bus	20:05	Harrisburg Bus Station	20h 15m	15:20	Gateway Station	No tags
Bus	21:10	Harrisburg Bus Station	1d 3h	23:25	Gateway Station	No tags

Last refresh of the prices: Today at 8:33 AM EST.

Compare 2 ways to travel from Harrisburg to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 20 hours 35 minutes and with fares starting at just R 1 434, it presents an excellent value for a comfortable ride.

4bus per day

20h 35mAverage duration

1158 kmDistance

29kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 1 434 - R 3 637	Average duration20h 35m	CO₂ emissions 29kg CO₂e
Train	Average priceR 2 591 - R 7 033	Average duration1d 10h	CO₂ emissions 105kg CO₂e

Where are the popular stops in Harrisburg and St. Louis?

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587 521 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

WiFi2.5

FlixBus

3.5/512 190 reviews

Staff4.1

Timeliness4

Cleanliness4.1

WiFi2.7

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Harrisburg to St. Louis by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Harrisburg to St. Louis?
The cheapest bus tickets from Harrisburg to St. Louis start at R 1 434. The average price for this route is around R 2 067. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Harrisburg to St. Louis?
The average bus journey time from Harrisburg to St. Louis is 20h 35m, covering a distance of 1158 km. The fastest bus gets you there in 18h 5m and is operated by Greyhound.
Which bus companies service the Harrisburg to St. Louis route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Harrisburg to St. Louis?
The earliest bus departs from Harrisburg to St. Louis at 02:30. And the latest bus departs at 21:10.
What are the CO₂ emissions for the bus trip from Harrisburg to St. Louis?
A bus trip from Harrisburg to St. Louis produces an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Harrisburg to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.
Which bus company has the best Wi-Fi from Harrisburg to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Harrisburg to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/02

No data

06/02

No data

Today

R 1 957

08/02

R 1 793

09/02

R 1 448

10/02

R 1 365

11/02

R 1 365

12/02

R 1 448

The cheapest trip from Harrisburg to St. Louis was searched and found on 10 Feb 2026 with a price of R 1 365

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to St. Louis as early as possible.

You can expect to pay from R 1 365 to R 3 487 for a bus ticket from Harrisburg to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 365, which is on 2026-02-10.