Find coaches from Harrisburg to St. Louis

Previously seen journeys

Next departures from Harrisburg to St. Louis on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Harrisburg Bus Station
Gateway StationNo tags
Greyhound
Harrisburg Bus Station
Gateway StationNo tags
Greyhound
Harrisburg Bus Station
Gateway StationNo tags
Greyhound
Harrisburg Bus Station
Gateway StationNo tags
Greyhound
Harrisburg Bus Station
Gateway StationNo tags

Accepted payments

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  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Harrisburg to St. Louis

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 20 hours 5 minutes and with fares starting at just US$103, it presents an excellent value for a comfortable ride.

5bus per day
20h 5mAverage duration
1158 kmDistance
29kgCO₂ emissions
Bus
Average priceUS$103 - US$267Average duration20h 5m
29kg CO₂e
Train
Average priceUS$175 - US$754Average duration1d 5h
105kg CO₂e

Bus Harrisburg to St. Louis: Trip Overview

Average ticket priceUS$155
Average bus trip duration20h 5m
Number of daily buses5
Earliest bus departure02:30
Distance1157 km
Latest bus departure21:10

Harrisburg to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Harrisburg to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Harrisburg to St. Louis.

Discover how much the bus trip from Harrisburg to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Harrisburg - St. Louis

  1. How much does a bus ticket from Harrisburg to St. Louis cost?

    The bus ticket price from Harrisburg to St. Louis starts at US$103. The best way to find cheap bus tickets from Harrisburg to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Harrisburg to St. Louis?

    The average travel time between Harrisburg and St. Louis is around 20h 5m, although the fastest bus will take about 17h 20m. This is the time it takes to travel the 1158 km that separates the two cities.

  3. How many daily bus connections are there between Harrisburg and St. Louis?

    The number of buses from Harrisburg to St. Louis can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Harrisburg to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Harrisburg to St. Louis?

    When taking the bus from Harrisburg to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
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30/10
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Today
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01/11
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02/11
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03/11
US$95
04/11
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05/11
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busbud logoThe cheapest trip from Harrisburg to St. Louis was searched and found on 03 Nov 2025 with a price of US$95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to St. Louis as early as possible.

You can expect to pay from US$95 to US$114 for a bus ticket from Harrisburg to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$95, which is on 2025-11-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Harrisburg to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Harrisburg to St. Louis.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Harrisburg to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Harrisburg to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Harrisburg to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from St. Louis to Harrisburg

You can also go to St. Louis by train

Train from Harrisburg to St. Louis

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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