Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Knoxville Bus Station | WJW Investments Bus Stop | CheapestFastest |
Last refresh of the prices: Yesterday at 9:09 PM EDT.
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Bus Knoxville, TN to Lexington, KY: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Knoxville Lexington recent customer reviews
It was going well but then it broke down and we had to wait for another bus to come from 2 hours away
Laurel T.
Awesome. Great
Jifin V.
Knoxville to Lexington Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Lexington.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Lexington.
Whether it is cheap bus tickets or more luxurious buses going to Lexington from Knoxville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Knoxville and Lexington?
Frequently asked questions for your trip Knoxville, TN - Lexington, KY
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Lexington, KY was searched and found on Oct 22, 2025 with a price of $29To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Lexington, KY, as early as possible.
You can expect to pay from $29 to $87 for a bus ticket from Knoxville, TN to Lexington, KY based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-10-25.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Lexington but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Lexington.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Lexington.
Make a music playlist for your bus ride from Knoxville to Lexington, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Chicago
- Bus Knoxville - Orlando
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Tampa
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
- Knoxville - Detroit
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Hartford - Knoxville
- Louisville - Knoxville
- Bus from New York City to Knoxville
- Bus Lexington - Knoxville
- Greenville - Knoxville
- Bus from Dallas to Knoxville
- Bus Cookeville - Knoxville
- Cincinnati - Knoxville
Popular Buses Connecting Lexington
Buses Leaving from Lexington
- Bus from Lexington to New York City
- Bus Lexington - Miami
- Lexington - Windsor
- Bus from Lexington to London
- Bus Lexington - London
- Lexington - Boston
- Bus from Lexington to Cincinnati
- Bus Lexington - Louisville
- Lexington - Atlanta
- Bus from Lexington to Nashville
- Bus Lexington - Chicago
- Lexington - Columbus
- Bus from Lexington to Knoxville
- Bus Lexington - Indianapolis
- Lexington - Detroit
Buses Going to Lexington
- Bus from Manchester to Lexington
- Bus Knoxville - Lexington
- Manchester - Lexington
- Bus from Atlanta to Lexington
- Bus Marathon - Lexington
- Charlotte - Lexington
- Bus from Cincinnati to Lexington
- Bus Chicago - Lexington
- Nashville - Lexington
- Bus from Columbus to Lexington
- Bus New York City - Lexington
- Indianapolis - Lexington
- Bus from Junction City to Lexington
- Bus Detroit - Lexington
- St. Louis - Lexington
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio