Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Heinrich-von-Stephan-Straße 4-6 | Perrache | Cheapest | ||||
 | Bus | ZOB | Lyon - Perrache Bus Station | Fastest | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Aéroport LYS | No tags | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Perrache | No tags | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Perrache | No tags |
Last refresh of the prices: 12/13/2025 CET.
Compare 2 ways to travel from Mannheim to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 6 hours 20 minutes and with fares starting at just R 591, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 569 - R 3 624 | Average duration13h 25m | 12kg CO₂e | ||
Carpool | Average priceR 591 - R 1 206 | Average duration6h 20m | 21kg CO₂e |
Where are the popular stops in Mannheim and Lyon?
Stops in Mannheim
- AHeinrich-von-Stephan-Straße 4-6, 68161 Mannheim, Germany
- BWilly-Brandt-Platz 17, 68161 Mannheim, Germany
- C
Uhlandstraße 7
Uhlandstraße 7, 68167 Mannheim, Germany
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- B
Lyon Airport
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Frequently asked questions about travelling from Mannheim to Lyon by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mannheim to Lyon?
The cheapest bus tickets from Mannheim to Lyon start at R 569. The average price for this route is around R 1 036. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mannheim to Lyon?
The average bus journey time from Mannheim to Lyon is 13h 25m, covering a distance of 497 km. The fastest bus gets you there in 9h and is operated by BlaBlaCar Bus.
Which bus companies service the Mannheim to Lyon route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Mannheim to Lyon?
The earliest bus departs from Mannheim to Lyon at 00:15. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Mannheim to Lyon?
A bus trip from Mannheim to Lyon produces an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Mannheim to Lyon?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11197 reviews.
Which bus company has the best Wi-Fi from Mannheim to Lyon?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Mannheim to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Mannheim to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Lyon was searched and found on 18 Dec 2025 with a price of R 717To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Lyon as early as possible.
You can expect to pay from R 717 to R 3 559 for a bus ticket from Mannheim to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 033, which is on 2025-12-25.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
