Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mendoza Terminal | Terminal de Ómnibus de Santiago del Estero | Cheapest | ||||
 | Bus | Mendoza Terminal | Terminal de Ómnibus de Santiago del Estero | Fastest | ||||
 | Bus | Mendoza Terminal | Terminal de Ómnibus de Santiago del Estero | No tags | ||||
| Bus | Mendoza Terminal | Terminal de Ómnibus de Santiago del Estero | No tags | ||||
| Bus | Mendoza Terminal | Terminal de Ómnibus de Santiago del Estero | No tags |
Last refresh of the prices: Last Wednesday at 2:01 PM -03.
Get from Mendoza to Santiago del Estero
The journey takes about 17 hours 10 minutes, and with fares starting at just R 1 362, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mendoza and Santiago del Estero?
Stops in Mendoza
- AAv. Gdor. Ricardo Videla, Mendoza, Argentina
- BAv. Gobernador Ricardo Videla , M5519 Mendoza, Argentina
- CAcceso A Aeropuerto Internacional Gabrielli F. J., Las Heras, Mendoza, Argentina
- DChile 1124, 5500 Mendoza, Argentina
- E
Parada de Autobuses de Mendoza - Nogoli
Nogoli 699, M5501HVC Godoy Cruz, Mendoza, Argentina - F
Vistalba 3020
Vistalba 3020, Godoy Cruz, Mendoza, Argentina
Stops in Santiago del Estero
- A
Terminal de Ómnibus de Santiago del Estero
Chacabuco, s/n, 4200 Santiago del Estero - BSta Fe 484, 4200 Santiago del Estero, Santiago del Estero, Argentina
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Frequently asked questions about travelling from Mendoza, AR to Santiago del Estero by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mendoza to Santiago del Estero?
The cheapest bus tickets from Mendoza to Santiago del Estero start at R 1 362. The average price for this route is around R 1 443. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mendoza to Santiago del Estero?
The average bus journey time from Mendoza to Santiago del Estero is 17h 10m, covering a distance of 718 km. The fastest bus gets you there in 16h 5m and is operated by Andesmar.
Which bus companies service the Mendoza to Santiago del Estero route?
Several major bus companies operate on this route with 2 buses available per day, including services from Andesmar, 20 de Junio, San Juan Mar del Plata, Pool de Los Andes, Tramat.
What is the earliest and latest departure time for the bus from Mendoza to Santiago del Estero?
The earliest bus departs from Mendoza to Santiago del Estero at 10:50. And the latest bus departs at 21:30.
What are the CO₂ emissions for the bus trip from Mendoza to Santiago del Estero?
A bus trip from Mendoza to Santiago del Estero produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Mendoza to Santiago del Estero?
According to Busbud customers, the highest-rated bus company on this route is Pool de Los Andes, with an average rating of 5.0 out of 5 stars based on 1 reviews.
Which bus company has the best Wi-Fi from Mendoza to Santiago del Estero?
Based on reviews on Busbud, the bus company 20 de Junio has the best Wi-Fi rating with a score of 2.3.
Which bus company offers the most punctual service from Mendoza to Santiago del Estero?
According to Busbud traveller reviews, the most punctual bus company on this route is 20 de Junio, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Mendoza to Santiago del Estero?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mendoza, AR to Santiago del Estero was searched and found on 04 Dec 2025 with a price of R 1 131To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza, AR to Santiago del Estero as early as possible.
You can expect to pay from R 1 131 to R 1 860 for a bus ticket from Mendoza, AR to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 233, which is on 2025-12-08.
