Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mendoza Terminal | Terminal de Ómnibus de Santiago del Estero | CheapestFastest |
Last refresh of the prices: Today at 5:53 PM -03.
Get from Mendoza to Santiago del Estero
The journey takes about 17 hours 10 minutes, and with fares starting at just $113, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mendoza and Santiago del Estero?
Stops in Mendoza
- AAv. Gdor. Ricardo Videla, Mendoza, Argentina
- BAv. Gobernador Ricardo Videla , M5519 Mendoza, Argentina
- CAcceso A Aeropuerto Internacional Gabrielli F. J., Las Heras, Mendoza, Argentina
- DChile 1124, 5500 Mendoza, Argentina
- E
Parada de Autobuses de Mendoza - Nogoli
Nogoli 699, M5501HVC Godoy Cruz, Mendoza, Argentina - F
Vistalba 3020
Vistalba 3020, Godoy Cruz, Mendoza, Argentina
Stops in Santiago del Estero
- A
Terminal de Ómnibus de Santiago del Estero
Chacabuco, s/n, 4200 Santiago del Estero - BSta Fe 484, 4200 Santiago del Estero, Santiago del Estero, Argentina
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Frequently asked questions about travelling from Mendoza, AR to Santiago del Estero by bus
How far is Mendoza from Santiago del Estero?
The distance between Mendoza and Santiago del Estero is approximately 717 km (445 miles).
What are the departure and arrival locations for buses traveling from Mendoza to Santiago del Estero?
Buses departing from Mendoza Terminal in Mendoza will take you to Terminal de Ómnibus de Santiago del Estero in Santiago del Estero.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mendoza, AR to Santiago del Estero was searched and found on Nov 26, 2025 with a price of $51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza, AR to Santiago del Estero, as early as possible.
You can expect to pay from $51 to $137 for a bus ticket from Mendoza, AR to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-11-26.
Usually Andesmar will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
Top travelled bus routes
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