Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Mesa Bus Stop | San Ysidro Bus terminal | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Mesa Bus Stop | San Ysidro Greyhound Bus Station | No tags |
Last refresh of the prices: Last Sunday at 6:49 AM MST.
Get from Mesa to San Ysidro
The journey takes about 14 hours 25 minutes, and with fares starting at just R 1 139, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mesa and San Ysidro?
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Compare bus companies
Based on 87488 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 139
Frequently asked questions about travelling from Mesa to San Ysidro, CA by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mesa to San Ysidro?
The cheapest bus tickets from Mesa to San Ysidro start at R 1 139. The average price for this route is around R 1 905. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mesa to San Ysidro?
The average bus journey time from Mesa to San Ysidro is 14h 25m, covering a distance of 494 km. The fastest bus gets you there in 16h 10m and is operated by Greyhound.
Which bus companies service the Mesa to San Ysidro route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Mesa to San Ysidro?
The earliest bus departs from Mesa to San Ysidro at 19:15. And the latest bus departs at 21:10.
What are the CO₂ emissions for the bus trip from Mesa to San Ysidro?
A bus trip from Mesa to San Ysidro produces an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to San Ysidro, CA was searched and found on 06 Jan 2026 with a price of R 1 061To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to San Ysidro, CA as early as possible.
