Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | TAPO | Santiago Tuxtla, Santiago Tuxtla Ver. | CheapestFastest | ||||
| Bus | TAPO | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags | ||||
| Bus | TAPO | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags | ||||
| Bus | Terminal del Norte | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags | ||||
| Bus | Terminal del Norte | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags |
Last refresh of the prices: 12/05/2025 CST.
Get from Mexico City to Santiago Tuxtla
The journey takes about 9 hours, and with fares starting at just R 1 329, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from Mexico City to Santiago Tuxtla by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mexico City to Santiago Tuxtla?
The cheapest bus tickets from Mexico City to Santiago Tuxtla start at R 1 329. The average price for this route is around R 1 405. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mexico City to Santiago Tuxtla?
The average bus journey time from Mexico City to Santiago Tuxtla is 9h, covering a distance of 416 km. The fastest bus gets you there in 7h 55m and is operated by ADO.
Which bus companies service the Mexico City to Santiago Tuxtla route?
Several major bus companies operate on this route with 5 buses available per day, including services from ADO, AU, Autobuses Adonai.
What is the earliest and latest departure time for the bus from Mexico City to Santiago Tuxtla?
The earliest bus departs from Mexico City to Santiago Tuxtla at 20:00. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Mexico City to Santiago Tuxtla?
A bus trip from Mexico City to Santiago Tuxtla produces an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Mexico City to Santiago Tuxtla?
According to Busbud customers, the highest-rated bus company on this route is ADO, with an average rating of 4.2 out of 5 stars based on 10002 reviews.
Which bus company has the best Wi-Fi from Mexico City to Santiago Tuxtla?
Based on reviews on Busbud, the bus company ADO has the best Wi-Fi rating with a score of 2.0.
Which bus company offers the most punctual service from Mexico City to Santiago Tuxtla?
According to Busbud traveller reviews, the most punctual bus company on this route is ADO, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Mexico City to Santiago Tuxtla?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ADO, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexico City to Santiago Tuxtla was searched and found on 14 Dec 2025 with a price of R 1 215To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to Santiago Tuxtla as early as possible.
You can expect to pay from R 1 215 to R 1 221 for a bus ticket from Mexico City to Santiago Tuxtla based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 215, which is on 2025-12-14.
