Find coaches from Milwaukee to Des Moines

Next departures

Next departures from Milwaukee to Des Moines on 1 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Milwaukee Bus Station, St. Paul & N6th road.
Des MoinesCheapestFastest
Greyhound Lines, Inc.
Milwaukee Bus Station, St. Paul & N6th road.
Des MoinesNo tags
Jefferson Lines
St. Paul & N5th
Des MoinesNo tags

Last refresh of the prices: Last Tuesday at 8:55 AM CDT.

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Get from Milwaukee to Des Moines

busbud logoThis route is served by bus only

The journey takes about 11 hours 30 minutes, and with fares starting at just US$57, it presents an excellent value for a comfortable ride.

3bus per day
11h 30mAverage duration
492 kmDistance
12kgCO₂ emissions

Bus Milwaukee to Des Moines: Trip Overview

Average ticket priceUS$123
Average bus trip duration11h 30m
Number of daily buses3
Earliest bus departure02:20
Distance492 km
Latest bus departure09:00

Milwaukee to Des Moines Bus

Busbud helps you find a bus from Milwaukee to Des Moines. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Milwaukee to Des Moines.

Discover how much the bus trip from Milwaukee to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milwaukee - Des Moines

  1. How much does a bus ticket from Milwaukee to Des Moines cost?

    The bus ticket price from Milwaukee to Des Moines starts at US$57. The best way to find cheap bus tickets from Milwaukee to Des Moines is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Milwaukee to Des Moines?

    The average travel time between Milwaukee and Des Moines is around 11h 30m, although the fastest bus will take about 11h 15m. This is the time it takes to travel the 496 km that separates the two cities.

  3. How many daily bus connections are there between Milwaukee and Des Moines?

    The number of buses from Milwaukee to Des Moines can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Milwaukee to Des Moines by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Milwaukee to Des Moines?

    When taking the bus from Milwaukee to Des Moines, you can travel comfortably and safely with Greyhound, Jefferson Lines.

  5. What are the departure and arrival stations when taking the bus from Milwaukee to Des Moines?

    Buses travelling between Milwaukee and Des Moines leave from Milwaukee Airport or Intermodal Station and arrive at Jefferson/Trailways Depot, 1514 East Grand Ave.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
US$91
30/10
US$132
Today
US$118
01/11
US$68
02/11
US$70
03/11
US$66
04/11
US$68
05/11
US$62
busbud logoThe cheapest trip from Milwaukee to Des Moines was searched and found on 05 Nov 2025 with a price of US$62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to Des Moines as early as possible.

You can expect to pay from US$62 to US$168 for a bus ticket from Milwaukee to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$62, which is on 2025-11-05.

Usually Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milwaukee and Des Moines!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Milwaukee to Des Moines.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Milwaukee to Des Moines will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Milwaukee to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Milwaukee by bus?

Bus from Des Moines to Milwaukee

Why choose Busbud?

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