Find coaches from Milwaukee to San Diego, CA, US

Previously seen journeys

Next departures from Milwaukee to San Diego on 30 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Milwaukee Mitchell MKE Airport
Downtown SD (Seaport)No tags
Greyhound + FlixBus
Milwaukee Mitchell MKE Airport
San Diego (Old Town-FlixBus)No tags
FlixBus + Greyhound
Milwaukee Mitchell MKE Airport
UCSD Health La Jolla StationNo tags
Greyhound + FlixBus
Milwaukee Bus Station, St. Paul & N6th road.
Balboa ParkNo tags
Greyhound + FlixBus
Milwaukee Bus Station, St. Paul & N6th road.
Downtown SD (Seaport)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Milwaukee to San Diego

busbud logoWe recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 2 days, 3 hours 53 minutes and with fares starting at just US$383, it presents an excellent value for a comfortable ride.

4train per day
2d 3hAverage duration
2791 kmDistance
254kgCO₂ emissions
Average priceUS$159 - US$472Average duration2d 16h
69kg CO₂e
Average priceUS$383 - US$526Average duration2d 3h
254kg CO₂e

Bus Milwaukee to San Diego, CA, US: Trip Overview

Average ticket priceUS$274
Average bus trip duration2d 16h
Number of daily buses15
Earliest bus departure05:30
Distance2774 km
Latest bus departure19:35

Milwaukee to San Diego Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Milwaukee to San Diego.

Bus service from Milwaukee to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Milwaukee to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Milwaukee - San Diego, CA, US

  1. How much does a bus ticket from Milwaukee to San Diego cost?

    The bus ticket price from Milwaukee to San Diego starts at US$159. The best way to find cheap bus tickets from Milwaukee to San Diego is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Milwaukee to San Diego?

    The average travel time between Milwaukee and San Diego is around 2d 16h, although the fastest bus will take about 2d 7h. This is the time it takes to travel the 2797 km that separates the two cities.

  3. How many daily bus connections are there between Milwaukee and San Diego?

    The number of buses from Milwaukee to San Diego can differ depending on the day of the week. On average, there are 15 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Milwaukee to San Diego by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Milwaukee to San Diego?

    When taking the bus from Milwaukee to San Diego, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from Milwaukee to San Diego?

    Buses travelling between Milwaukee and San Diego leave from Milwaukee Airport or Intermodal Station and arrive at Mission Valley Sheraton, Old Town Courtyard Marriot, Downtown Holiday Inn.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
No data
29/10
US$265
Today
No data
31/10
No data
01/11
No data
02/11
No data
03/11
No data
04/11
No data
busbud logoThe cheapest trip from Milwaukee to San Diego, CA, US was searched and found on 29 Oct 2025 with a price of US$265

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to San Diego, CA, US as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Milwaukee to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Milwaukee to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Milwaukee to San Diego that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milwaukee to San Diego.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Milwaukee to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milwaukee by bus?

Bus from San Diego, CA, US to Milwaukee

You can also go to San Diego, CA, US by train

Train from Milwaukee to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Milwaukee

Buses Leaving from Milwaukee

Buses Going to Milwaukee

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego