Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus Station | Spartanburg | CheapestFastest |
Last refresh of the prices: Last Saturday at 7:48 AM EST.
Get from Myrtle Beach to Spartanburg
The journey takes about 16 hours 20 minutes, and with fares starting at just R 1 478, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Spartanburg?
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Compare bus companies
Based on 87434 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 478
Frequently asked questions about travelling from Myrtle Beach to Spartanburg by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Myrtle Beach to Spartanburg?
The cheapest bus tickets from Myrtle Beach to Spartanburg start at R 1 478. The average price for this route is around R 1 692. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Myrtle Beach to Spartanburg?
The average bus journey time from Myrtle Beach to Spartanburg is 16h 20m, covering a distance of 322 km. The fastest bus gets you there in 16h 20m and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Spartanburg route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Spartanburg?
The earliest bus departs from Myrtle Beach to Spartanburg at 13:55. And the latest bus departs at 13:55.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Spartanburg?
A bus trip from Myrtle Beach to Spartanburg produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Spartanburg was searched and found on 15 Dec 2025 with a price of R 1 389To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Spartanburg as early as possible.
You can expect to pay from R 1 389 to R 2 872 for a bus ticket from Myrtle Beach to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 792, which is on 2025-12-19.
