Find coaches from Spartanburg to Indianapolis

Next bus departures

Next departures from Spartanburg to Indianapolis on 12 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Spartanburg
Indianapolis Bus StationCheapest
Greyhound Lines, Inc. + FlixBus
Bus
Spartanburg
Downtown Transit CenterFastest
FlixBus + Greyhound Lines, Inc.
Bus
Spartanburg
Indianapolis Bus StationNo tags
FlixBusBus
Spartanburg
Downtown Transit CenterNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Spartanburg
Downtown Transit CenterNo tags

Last refresh of the prices: Today at 9:23 AM EST.

Compare 2 ways to travel from Spartanburg to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 17 hours 5 minutes and with fares starting at just R 1 507, it presents an excellent value for a comfortable ride.

6bus per day
17h 5mAverage duration
645 kmDistance
16kgCO₂ emissions
Bus
Average priceR 1 507 - R 4 610Average duration17h 5m
16kg CO₂e
Train
Average priceR 5 172 - R 5 172Average duration1d 2h
59kg CO₂e

Frequently asked questions about travelling from Spartanburg to Indianapolis by bus

  1. How much does a bus ticket from Spartanburg to Indianapolis cost?

    The bus ticket price from Spartanburg to Indianapolis starts at R 1 507. The best way to find cheap bus tickets from Spartanburg to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Spartanburg to Indianapolis?

    The average travel time between Spartanburg and Indianapolis is around 17h 5m, although the fastest bus will take about 15h 5m. This is the time it takes to travel the 654 km that separates the two cities.

  3. How many daily bus connections are there between Spartanburg and Indianapolis?

    The number of buses from Spartanburg to Indianapolis can differ depending on the day of the week. On average, there are 6 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Spartanburg to Indianapolis by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Spartanburg to Indianapolis?

    When taking the bus from Spartanburg to Indianapolis, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Spartanburg to Indianapolis?

    Buses travelling between Spartanburg and Indianapolis leave from Super Acapulco or Spartanburg Bus Stop and arrive at Greyhound Amtrak Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
No data
10/11
No data
Today
No data
12/11
R 2 321
13/11
R 1 978
14/11
No data
15/11
No data
16/11
No data
busbud logoThe cheapest trip from Spartanburg to Indianapolis was searched and found on 13 Nov 2025 with a price of R 1 978

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Indianapolis as early as possible.

You can expect to pay from R 1 978 to R 2 620 for a bus ticket from Spartanburg to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 978, which is on 2025-11-13.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Spartanburg to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

People from around the world trust Busbud

‌

Popular Buses Connecting Spartanburg

Buses Leaving from Spartanburg

Buses Going to Spartanburg

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis