- Port Saint Lucie to Key West buses
Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Port St Lucie (Park & Ride) | Key West Bus Station | No tags | ||||
![]() | Bus | Port St Lucie (Park & Ride) | Caroline St | No tags | ||||
![]() | Bus | Port St Lucie (Park & Ride) | Key West Bus Station | No tags | ||||
![]() | Bus | Port St Lucie (Park & Ride) | Caroline St | No tags | ||||
FlixBus + Greyhound | Bus | Port St Lucie (Park & Ride) | Key West Bus Station | No tags |
Get from Port Saint Lucie to Key West
The journey takes about 12 hours 10 minutes, and with fares starting at just R 1 146, it presents an excellent value for a comfortable ride.
Where are the popular stops in Port Saint Lucie and Key West?
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Compare bus companies
Based on 11648 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 129
Frequently asked questions about travelling from Port Saint Lucie to Key West by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Port Saint Lucie to Key West?
The cheapest bus tickets from Port Saint Lucie to Key West start at R 1 146. The average price for this route is around R 1 240. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Port Saint Lucie to Key West?
The average bus journey time from Port Saint Lucie to Key West is 12h 10m, covering a distance of 330 km. The fastest bus gets you there in 8h 20m and is operated by FlixBus.
Which bus companies service the Port Saint Lucie to Key West route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Port Saint Lucie to Key West?
The earliest bus departs from Port Saint Lucie to Key West at 03:20. And the latest bus departs at 03:20.
What are the CO₂ emissions for the bus trip from Port Saint Lucie to Key West?
A bus trip from Port Saint Lucie to Key West produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.






