Next departures from Prague to Brno on 10 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Prague (Central Bus Station Florenc)
Hotelu Grand
Cheapest
Bus
Tomíčkova
Hotelu Grand
Fastest
Vlak společnosti Gepard Express
Bus
PRG Airport
Hotelu Grand
No tags
Bus
Florenc
ÚAN Zvonařka
No tags
Bus
Praha [*CZ],,ÚAN Florenc, platform 6, Prague
hotel GRAND, Brno
No tags
Next departures from Prague to Brno on 11 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Prague (Central Bus Station Florenc)
Hotelu Grand
Cheapest
Maksymiuk FOP
Bus
Florenc
Brno Petrol Station Omv
Fastest
Vlak společnosti Gepard Express
Bus
PRG Airport
Hotelu Grand
No tags
Bus
Praha [*CZ],,ÚAN Florenc, platform 6, Prague
hotel GRAND, Brno
No tags
Bus
Florenc
Hotelu Grand
No tags
Next departures from Prague to Brno on 12 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Prague (Central Bus Station Florenc)
Hotelu Grand
Cheapest
Bus
Tomíčkova
Hotelu Grand
Fastest
Vlak společnosti Gepard Express
Bus
PRG Airport
Hotelu Grand
No tags
Bus
Florenc
ÚAN Zvonařka
No tags
Bus
Praha [*CZ],,ÚAN Florenc, platform 6, Prague
hotel GRAND, Brno
No tags
Next departures from Prague to Brno on 13 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Prague (Central Bus Station Florenc)
Hotelu Grand
Cheapest
Bus
Tomíčkova
Hotelu Grand
Fastest
Vlak společnosti Gepard Express
Bus
PRG Airport
Hotelu Grand
No tags
Bus
Praha [*CZ],,ÚAN Florenc, platform 19, Prague
Brno ÚAN Zvonařka
No tags
Bus
Florenc
ÚAN Zvonařka
No tags
Next departures from Prague to Brno on 14 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Prague (Central Bus Station Florenc)
Hotelu Grand
Cheapest
Maksymiuk FOP
Bus
Florenc
Brno Petrol Station Omv
Fastest
Vlak společnosti Gepard Express
Bus
PRG Airport
Hotelu Grand
No tags
Bus
Florenc
ÚAN Zvonařka
No tags
Bus
Praha [*CZ],,ÚAN Florenc, platform 6, Prague
hotel GRAND, Brno
No tags
Last refresh of the prices: Today at 5:34 AM CET.
Compare 2 ways to travel from Prague to Brno
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Brno. The journey takes about 2 hours 40 minutes and with fares starting at just R 158, it presents an excellent value for a comfortable ride.
Based on 11545 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 158
Based on 1058 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the value for money but often complained with the Wi-Fi. RegioJet ticket prices on this trip start at R 216
Gepard Express offers 5 daily departures, and you can find tickets starting at R 473. The quickest ride takes around 147. Gepard Express offers a cost-effective solution to get you where you need to be.
Based on 152 reviews, the company was rated 4.5 stars on Busbud. Travellers were especially satisfied with the temperature and the seats but often complained with the Wi-Fi. Slovak Lines ticket prices on this trip start at R 308
A-Express offers 1 daily buses from Prague to Brno. Though the average price for this trip is R 340, you can find tickets starting at R 338. The trip between the two cities usually takes about 155.
Musil Tour offers 1 daily departures, and you can find tickets starting at R 257. The quickest ride takes around 150. Musil Tour offers a cost-effective solution to get you where you need to be.
Based on 2 reviews, Avtokombinat-1 OOO was rated 3 stars for this trip. Avtokombinat-1 OOO ticket prices on this trip start at R 313, with the trip lasting on average 190.
A good way to travel this route is with Maksymiuk FOP buses. The company offers 1 daily departures, with ticket prices starting at R 453 and the shortest trip taking about 120. Maksymiuk FOP gets you where you want to go for a fair price.
Based on 20 reviews, the company was rated 4.5 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the power outlets. IC Bus ticket prices on this trip start at R 299
Monobus offers 1 daily departures, and you can find tickets starting at R 263. The quickest ride takes around 200. Monobus offers a cost-effective solution to get you where you need to be.
Based on 6 reviews, Turancar was rated 4 stars for this trip. Turancar ticket prices on this trip start at R 339, with the trip lasting on average 155.
Based on 491 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. Infobus ticket prices on this trip start at R 225
Frequently asked questions about travelling from Prague to Brno by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Prague to Brno?
The cheapest bus tickets from Prague to Brno start at R 158. The average price for this route is around R 269. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Prague to Brno?
The average bus journey time from Prague to Brno is 2h 40m, covering a distance of 186 km. The fastest bus gets you there in 2h and is operated by Maksymiuk FOP.
Which bus companies service the Prague to Brno route?
What is the earliest and latest departure time for the bus from Prague to Brno?
The earliest bus departs from Prague to Brno at 01:45. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Prague to Brno?
A bus trip from Prague to Brno produces an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Prague to Brno?
According to Busbud customers, the highest-rated bus company on this route is Slovak Lines, with an average rating of 4.5 out of 5 stars based on 151 reviews.
Which bus company has the best Wi-Fi from Prague to Brno?
Based on reviews on Busbud, the bus company Slovak Lines has the best Wi-Fi rating with a score of 4.0.
Which bus company offers the most punctual service from Prague to Brno?
According to Busbud traveller reviews, the most punctual bus company on this route is IC Bus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brno?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is IC Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
05/12
R 261
06/12
R 261
Today
R 166
08/12
R 114
09/12
R 114
10/12
R 114
11/12
R 114
12/12
R 114
The cheapest trip from Prague to Brno was searched and found on 08 Dec 2025 with a price of R 114
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brno as early as possible.
You can expect to pay from R 114 to R 2 899 for a bus ticket from Prague to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at R 114, which is on 2025-12-08.
What's the cheapest way to go from Prague to Brno?
The bus is the cheapest travel choice for this destination