Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Florenc | Busparkplatz Landenberg, 4 Werftestrasse | CheapestFastest | ||||
 | Bus
| Prague (Central Bus Station Florenc) | Luzern | No tags | ||||
| Bus
| Prague (Central Bus Station Florenc) | Luzern | No tags | ||||
| Bus
| Prague (Central Bus Station Florenc) | Luzern, Neuenkirch | No tags | ||||
| Bus
| Prague (Main Station - parking) | Luzern | No tags | ||||
| Bus
| Prague (Main Station - parking) | Luzern | No tags | ||||
| Bus
| Prague (Main Station - parking) | Luzern, Neuenkirch | No tags | ||||
| Bus
| Prague (Na Knížecí) | Luzern | No tags |
Last refresh of the prices: Today at 9:18 AM CEST.
Get from Prague to Lucerne
The journey takes about 16 hours 50 minutes, and with fares starting at just COP 162 157, it presents an excellent value for a comfortable ride.
Bus stations and stops in Prague and Lucerne
Stops in Prague
- A
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - D
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Lucerne
- A
Lucerne Carparkplatz Inseliquai
Inseliquai, 6005 Luzern, Switzerland - B
Luzern Omnibusbahnhof
Luzern,, Switzerland - C
Parking Bus Inselipark
Europaplatz, 6005 Luzern, Switzerland
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Frequently asked questions about travelling from Prague to Lucerne by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Prague to Lucerne?
The cheapest bus tickets from Prague to Lucerne start at COP 162 157. The average price for this route is around COP 295 625. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Prague to Lucerne?
The average bus journey time from Prague to Lucerne is 16h 50m, covering a distance of 560 km. The fastest bus gets you there in 10h 25m and is operated by RegioJet.
Which bus companies service the Prague to Lucerne route?
What is the earliest and latest departure time for the bus from Prague to Lucerne?
The earliest bus departs from Prague to Lucerne at 06:15. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Prague to Lucerne?
A bus trip from Prague to Lucerne produces an estimated 13.99955 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Prague to Lucerne?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1106 reviews.
Which bus company has the best Wi-Fi from Prague to Lucerne?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.7.
Which bus company offers the most punctual service from Prague to Lucerne?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Lucerne?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Lucerne was searched and found on 10 Sept 2026 with a price of COP 162 253To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Lucerne as early as possible.
You can expect to pay from COP 162 253 to COP 528 484 for a bus ticket from Prague to Lucerne based on the last 2 days. You can expect to find the cheapest price for the trip at COP 227 791, which is on 2026-09-11.
