Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Puebla - Stop | Mexicali Centro Civico - Stop | CheapestFastest | ||||
 | Bus | Puebla Central Bus Station | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | No tags |
Last refresh of the prices: Today at 10:21 AM CST.
Get from Puebla to Mexicali
The journey takes about 1 day, 18 hours 3 minutes, and with fares starting at just R 2 111, it presents an excellent value for a comfortable ride.
Where are the popular stops in Puebla and Mexicali?
Stops in Puebla
- A
Terminal de Autobuses
Blvd. Norte No. 4222 (Col. Las Cuartillas), 72080 Puebla - B
Blvd. Carmen Serdán & Calle 27 Nte.
Blvd. Carmen Serdán & Calle 27 Nte., Sta María la Rivera, 72010 Puebla, Pue., Mexico
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
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Frequently asked questions about travelling from Puebla, PUE to Mexicali by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Puebla to Mexicali?
The cheapest bus tickets from Puebla to Mexicali start at R 2 111. The average price for this route is around R 2 132. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Puebla to Mexicali?
The average bus journey time from Puebla to Mexicali is 1d 18h, covering a distance of 2288 km. The fastest bus gets you there in 1d 18h and is operated by ACN Autobuses.
Which bus companies service the Puebla to Mexicali route?
Several major bus companies operate on this route with 1 buses available per day, including services from Autotravel, ACN Autobuses, AU, Futura, Elite, Autobuses Adonai.
What is the earliest and latest departure time for the bus from Puebla to Mexicali?
The earliest bus departs from Puebla to Mexicali at 06:55. And the latest bus departs at 20:00.
What are the CO₂ emissions for the bus trip from Puebla to Mexicali?
A bus trip from Puebla to Mexicali produces an estimated 57 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Puebla to Mexicali?
According to Busbud customers, the highest-rated bus company on this route is AU, with an average rating of 3.8 out of 5 stars based on 874 reviews.
Which bus company has the best Wi-Fi from Puebla to Mexicali?
Based on reviews on Busbud, the bus company ACN Autobuses has the best Wi-Fi rating with a score of 1.9.
Which bus company offers the most punctual service from Puebla to Mexicali?
According to Busbud traveller reviews, the most punctual bus company on this route is AU, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Puebla to Mexicali?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is AU, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Puebla, PUE to Mexicali was searched and found on 18 Dec 2025 with a price of R 2 302To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Puebla, PUE to Mexicali as early as possible.
You can expect to pay from R 2 302 to R 4 332 for a bus ticket from Puebla, PUE to Mexicali based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 302, which is on 2025-12-18.
Usually ACN Autobuses will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
