Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Puebla - Stop | Mexicali Centro Civico - Stop | CheapestFastest | ||||
 | Bus | Puebla Central Bus Station | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | No tags |
Last refresh of the prices: Last Wednesday at 12:08 AM CST.
Get from Puebla to Mexicali
The journey takes about 1 day, 18 hours 3 minutes, and with fares starting at just $177, it presents an excellent value for a comfortable ride.
Where are the popular stops in Puebla and Mexicali?
Stops in Puebla
- A
Terminal de Autobuses
Blvd. Norte No. 4222 (Col. Las Cuartillas), 72080 Puebla - B
Blvd. Carmen Serdán & Calle 27 Nte.
Blvd. Carmen Serdán & Calle 27 Nte., Sta María la Rivera, 72010 Puebla, Pue., Mexico
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
Compare bus companies
Frequently asked questions about travelling from Puebla, PUE to Mexicali by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Puebla to Mexicali?
The cheapest bus tickets from Puebla to Mexicali start from $177. The average price for this route is around $220. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Puebla to Mexicali?
The average bus travel time from Puebla to Mexicali is 1d 18h, covering a distance of 2288 km. The quickest bus can get you there in 1d 18h and is operated by ACN Autobuses.
Which bus companies service the Puebla to Mexicali route?
Several major bus companies operate on this route with 1 buses available per day, including services from ACN Autobuses, Autotravel, AU, Futura, Elite, Autobuses Adonai.
What are the earliest and latest departure times for the bus from Puebla to Mexicali?
The earliest bus departs from Puebla to Mexicali at 2:00pm. And the latest bus departs at 8:15pm.
What are the CO₂ emissions for the bus trip from Puebla to Mexicali?
A bus trip from Puebla to Mexicali generates an estimated 57 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Puebla to Mexicali?
According to Busbud customers, the highest-rated bus company on this route is AU, with an average rating of 3.8 out of 5 stars based on 885 reviews.
Which bus company has the best Wi-Fi from Puebla to Mexicali?
Based on Busbud reviews, the bus company ACN Autobuses has the highest Wi-Fi rating with a score of 1.9.
Which bus company has the best on-time performance from Puebla to Mexicali?
According to Busbud traveller reviews, the most punctual bus company on this route is AU, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Puebla to Mexicali?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is AU, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Puebla, PUE to Mexicali was searched and found on Jan 8, 2026 with a price of $220To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Puebla, PUE to Mexicali, as early as possible.
You can expect to pay from $220 to $360 for a bus ticket from Puebla, PUE to Mexicali based on the last 2 days. You can expect to find the cheapest price for the trip at $221 which is on 2026-01-12.
