Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | San Diego (Old Town-FlixBus) | Jacksonville Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | UCSD Health La Jolla Station | Jacksonville Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Diego (Old Town-FlixBus) | Jacksonville Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | UCSD Health La Jolla Station | Jacksonville Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Bus Stop | Jacksonville Bus Station | No tags |
Last refresh of the prices: Last Thursday at 11:48 PM PST.
Compare 2 ways to travel from San Diego to Jacksonville
Among the sustainable travel choices, the Bus stands out as a good way to reach Jacksonville. The journey takes about 2 days, 14 hours 15 minutes and with fares starting at just R 2 096, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Diego and Jacksonville?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Stops in Jacksonville
- A
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - B3570 Clifford Ln, Jacksonville, FL 32209, USA
- C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Frequently asked questions about travelling from San Diego, CA, US to Jacksonville, FL by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Diego to Jacksonville?
The cheapest bus tickets from San Diego to Jacksonville start at R 2 096. The average price for this route is around R 5 719. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Diego to Jacksonville?
The average bus journey time from San Diego to Jacksonville is 2d 14h, covering a distance of 3363 km. The fastest bus gets you there in 2d 10h and is operated by FlixBus.
Which bus companies service the San Diego to Jacksonville route?
What is the earliest and latest departure time for the bus from San Diego to Jacksonville?
The earliest bus departs from San Diego to Jacksonville at 07:35. And the latest bus departs at 19:35.
What are the CO₂ emissions for the bus trip from San Diego to Jacksonville?
A bus trip from San Diego to Jacksonville produces an estimated 84 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Diego to Jacksonville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.
Which bus company has the best Wi-Fi from San Diego to Jacksonville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from San Diego to Jacksonville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Diego to Jacksonville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego, CA, US to Jacksonville, FL was searched and found on 02 Feb 2026 with a price of R 4 393To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Jacksonville, FL as early as possible.
You can expect to pay from R 4 393 to R 9 125 for a bus ticket from San Diego, CA, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at R 4 393, which is on 2026-02-02.
What's the cheapest way to go from San Diego, CA, US to Jacksonville, FL?
The Bus is the cheapest travel choice for this destination
