Find coaches from San Diego, CA, US to Santa Ana, US

Next departures

Next departures from San Diego to Santa Ana on 1 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		San Diego (Old Town-FlixBus)
    		UC Irvine (Crawford Hall)Cheapest
    FlixBus
      		UCSD Health La Jolla Station
      		UC Irvine (Crawford Hall)Fastest
      FlixBus
        		San Diego (Old Town-FlixBus)
        		Anaheim Regional Transportation Intermodal CenterNo tags
        Greyhound Lines, Inc.
          		Greyhound Bus Stop
          		Anaheim Regional Transportation Intermodal CenterNo tags
          Los Limousines
            		Cross Border Xpress CBX (USA)
            		Santa Ana E Santa Ana BlvdNo tags

            Last refresh of the prices: Today at 6:09 AM PDT.

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            Get from San Diego to Santa Ana

            This route is served by bus only

            The journey takes about 2 hours 5 minutes, and with fares starting at just US$21, it presents an excellent value for a comfortable ride.

            20bus per day
            2h 5mAverage duration
            122 kmDistance
            3kgCO₂ emissions

            Bus San Diego, CA, US to Santa Ana, US: Trip Overview

            Average ticket priceUS$44
            Average bus trip duration2h 5m
            Number of daily buses20
            Earliest bus departure00:30
            Distance122 km
            Latest bus departure22:30

            San Diego to Santa Ana Bus

            With Busbud, comparing and booking tickets for a bus from San Diego to Santa Ana is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from San Diego to Santa Ana from the most reliable bus companies operating this trip.

            From cheap bus tickets to more luxurious buses travelling from San Diego to Santa Ana, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip San Diego, CA, US - Santa Ana, US

            1. How much does a bus ticket from San Diego to Santa Ana cost?

              The bus ticket price from San Diego to Santa Ana starts at US$21. The best way to find cheap bus tickets from San Diego to Santa Ana is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from San Diego to Santa Ana?

              The average travel time between San Diego and Santa Ana is around 2h 5m, although the fastest bus will take about 1h 15m. This is the time it takes to travel the 133 km that separates the two cities.

            3. How many daily bus connections are there between San Diego and Santa Ana?

              The number of buses from San Diego to Santa Ana can differ depending on the day of the week. On average, there are 20 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Diego to Santa Ana by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from San Diego to Santa Ana?

              When taking the bus from San Diego to Santa Ana, you can travel comfortably and safely with Los Limousines, FlixBus, Greyhound.

            5. What are the departure and arrival stations when taking the bus from San Diego to Santa Ana?

              Buses travelling between San Diego and Santa Ana leave from Mission Valley Sheraton or Old Town Courtyard Marriot and arrive at Santa Ana Greyhound Bus Station, 602 S Main St.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            29/10
            US$21
            30/10
            US$21
            Today
            US$20
            01/11
            US$15
            02/11
            US$16
            03/11
            US$15
            04/11
            US$17
            05/11
            US$17
            busbud logoThe cheapest trip from San Diego, CA, US to Santa Ana, US was searched and found on 01 Nov 2025 with a price of US$15

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Santa Ana, US as early as possible.

            You can expect to pay from US$15 to US$44 for a bus ticket from San Diego, CA, US to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$15, which is on 2025-11-01.

            Usually Los Limousines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from San Diego to Santa Ana.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Santa Ana, get comfy and count the stars.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Santa Ana that are otherwise impossible to come by with a plane.

            Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Santa Ana while indulging in miles on end of beautiful scenic views.

            Did you know?

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            Will you be returning to San Diego, CA, US by bus?

            Bus from Santa Ana, US to San Diego, CA, US

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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