What is the travel distance from San Diego to Santa Ana?

San Diego and Santa Ana are 83 miles (133 km) apart.

What are the departure and arrival stations when taking the bus from San Diego to Santa Ana?

The majority of buses traveling from San Diego to Santa Ana start their journey at Mission Valley Sheraton and wind up at Santa Ana Greyhound Bus Station. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

Bus San Diego to Santa Ana from $16 | Compare & Save up to 60%

ThuJul 24

from $24

FriJul 25

from $25

SatJul 26

from $24

SunJul 27

from $25

MonJul 28

from $24

TueJul 29

from $24

WedJul 30

from $24

ThuJul 31

Cheap buses leaving Friday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: July 25 at 6:35pm
Departure city: San Diego
Departure location: San Diego (Old Town-FlixBus)
Arrival time: July 25 at 8:15pm
Destination city: Santa Ana
Destination location: UC Irvine (Crawford Hall)
Operated by: FlixBus
Vehicle: BusDuration: 1h 40m
This trip is recommended because it is: Fastest
Departure time: July 25 at 12:40pm
Departure city: San Diego
Departure location: UCSD Health La Jolla Station
Arrival time: July 25 at 1:50pm
Destination city: Santa Ana
Destination location: UC Irvine (Crawford Hall)
Operated by: FlixBus
Vehicle: BusDuration: 1h 10m
Departure time: July 25 at 8:10am
Departure city: San Diego
Departure location: San Diego (Old Town-FlixBus)
Arrival time: July 25 at 10:20am
Destination city: Santa Ana
Destination location: Anaheim Regional Transportation Intermodal Center
Operated by: FlixBus
Vehicle: BusDuration: 2h 10m
Departure time: July 25 at 2:00pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: July 25 at 4:20pm
Destination city: Santa Ana
Destination location: Anaheim Regional Transportation Intermodal Center
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 2h 20m
Departure time: July 25 at 2:00am
Departure city: San Diego
Departure location: Cross Border Xpress CBX (USA)
Arrival time: July 25 at 4:15am
Destination city: Santa Ana
Destination location: Santa Ana E Santa Ana Blvd
Operated by: Los Limousines
Vehicle: BusDuration: 2h 15m

Accepted payments

Compare 2 ways to go from San Diego to Santa Ana.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$23 - $46	Average Duration2h 15m	CO₂ emissions 4kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Shuttle	Average Price$92 - $92	Average Duration9h 10m	CO₂ emissions 4kg CO₂e4 out of 5 stars

Busbud recommends taking the bus from San Diego to Santa Ana

Among the sustainable travel choices, the bus stands out as the good way to reach Santa Ana. The journey takes about 2 hours 15 minutes and with fares starting at just $23, it presents an excellent value for a comfortable ride.

21bus per day

2h 15mAverage Duration

$23Cheapest ticket

4kgCO₂ emissions

Bus San Diego, CA, US to Santa Ana, US: Trip Overview

Average ticket price$45

Average bus trip duration2h 15m

Number of daily buses21

Earliest bus departure12:30am

Distance98 miles (157 km)

Latest bus departure10:30pm

Compare bus companies

Los Limousines

3.5/5231 reviews

Staff4.2

Timeliness2.7

Cleanliness3.8

Wifi2.8

Based on 231 reviews, the company was rated 3.3 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the timeliness. Los Limousines ticket prices on this trip start at $43

Los Limousines San Diego Santa Ana recent customer reviews

the bus was early 1/2 hour and arrived to the destination 15 minutes early this was nice.

Rafael G.

April 14, 2025

FlixBus

3.5/59,675 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,130 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound San Diego Santa Ana recent customer reviews

Already filled a complaint against your bus company with Department of Consumer Affairs, Department of Transportation, and Better Business Bureau.

Peter N.

October 21, 2018

I had to wait more than 3 hours because my scheduled bus was delayed. I almost cured out loud.

Toan T.

August 11, 2018

Price and people were good but : Old bus No wifi Must print ticket .... come on, we are in 2017!!!! Even at home in Quebec, we can show the electronic ticket in greyhounds bus!!!

Isabelle R.

June 14, 2017

Las Vegas Shuttles

3.5/545 reviews

Staff4.5

Timeliness2.2

Cleanliness4.7

Wifi3.2

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

San Diego to Santa Ana Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Santa Ana is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to Santa Ana from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from San Diego to Santa Ana, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in San Diego and Santa Ana?

Stops in San Diego

A - Mission Valley Sheraton

B - Old Town Courtyard Marriot

C - Downtown Holiday Inn

D - Greyhound Station

E - Market St. & Park Blvd

F - San Ysidro McDonald's

Stops in Santa Ana

A - Santa Ana Greyhound Bus Station

B - 602 S Main St

Frequently asked questions for your trip San Diego, CA, US - Santa Ana, US

What is the travel distance from San Diego to Santa Ana?
What are the departure and arrival stations when taking the bus from San Diego to Santa Ana?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07/20

$20

07/21

$19

Today

$19

07/23

$16

07/24

$16

07/25

$17

07/26

$17

07/27

$18

The cheapest trip from San Diego, CA, US to Santa Ana, US was searched and found on Jul 23, 2025 with a price of $16

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Santa Ana, US, as early as possible.

You can expect to pay from $16 to $43 for a bus ticket from San Diego, CA, US to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at $16 which is on 2025-07-23.

Usually LLIO will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to Santa Ana.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Santa Ana, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Santa Ana that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Santa Ana while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to San Diego, CA, US by bus?

Bus from San Diego, CA, US to Santa Ana, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Bus Tickets from San Diego, CA, US to Santa Ana, US

One passenger / one way

Cheap buses leaving Friday

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from San Diego to Santa Ana.

Bus San Diego, CA, US to Santa Ana, US: Trip Overview

Compare bus companies

Los Limousines San Diego Santa Ana recent customer reviews

Greyhound San Diego Santa Ana recent customer reviews

San Diego to Santa Ana Bus

Where are the popular stops in San Diego and Santa Ana?

Frequently asked questions for your trip San Diego, CA, US - Santa Ana, US

What is the travel distance from San Diego to Santa Ana?

What are the departure and arrival stations when taking the bus from San Diego to Santa Ana?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to San Diego, CA, US by bus?

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting San Diego

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Popular Buses Connecting Santa Ana

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