Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Mission St & Fremont St | AMTRAK Station | CheapestFastest | |||||
| Mission St & Fremont St | Cal Poly Vista Grande Dining Complex | No tags | |||||
| Mission St & Fremont St | AMTRAK Station | No tags | |||||
| Mission St & Fremont St | AMTRAK Station | No tags |
Last refresh of the prices: Last Wednesday at 11:42 PM PST.
Get from San Francisco to San Luis Obispo
The journey takes about 4 hours 30 minutes, and with fares starting at just R 764, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Francisco and San Luis Obispo?
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
Stops in San Luis Obispo
- A1730 Santa Rosa St, San Luis Obispo, CA 93401, USA
- B
San Luis Obispo Bus Stop
1460 Calle Joaquin, San Luis Obispo, CA 93405, USA
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Frequently asked questions about travelling from San Francisco, US to San Luis Obispo by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Francisco to San Luis Obispo?
The cheapest bus tickets from San Francisco to San Luis Obispo start at R 764. The average price for this route is around R 1 076. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Francisco to San Luis Obispo?
The average bus journey time from San Francisco to San Luis Obispo is 4h 30m, covering a distance of 319 km. The fastest bus gets you there in 4h 20m and is operated by FlixBus.
Which bus companies service the San Francisco to San Luis Obispo route?
What is the earliest and latest departure time for the bus from San Francisco to San Luis Obispo?
The earliest bus departs from San Francisco to San Luis Obispo at 08:20. And the latest bus departs at 12:05.
What are the CO₂ emissions for the bus trip from San Francisco to San Luis Obispo?
A bus trip from San Francisco to San Luis Obispo produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Francisco to San Luis Obispo?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which bus company has the best Wi-Fi from San Francisco to San Luis Obispo?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from San Francisco to San Luis Obispo?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Francisco to San Luis Obispo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Francisco, US to San Luis Obispo was searched and found on 15 Dec 2025 with a price of R 831To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Luis Obispo as early as possible.
You can expect to pay from R 831 to R 4 861 for a bus ticket from San Francisco, US to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at R 831, which is on 2025-12-15.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
