Bus Tickets from San Francisco, US to San Luis Obispo

Next departures

Next departures for San Francisco to San Luis Obispo on September 16
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
409 Townsend St, SF
San Luis ObispoCheapestFastest
Amtrak
Mission St & Fremont St
Cal Poly Vista Grande Dining ComplexNo tags
Amtrak
Mission St & Fremont St
Cal Poly Vista Grande Dining ComplexNo tags
Amtrak
Mission St & Fremont St
Cal Poly Vista Grande Dining ComplexNo tags
Amtrak
Mission St & Fremont St
AMTRAK StationNo tags

Accepted payments

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Bus San Francisco, US to San Luis Obispo: Trip Overview

Average ticket price$46
Average bus trip duration4h 30m
Number of daily buses1
Earliest bus departure8:20am
Distance198 miles (318 km)
Latest bus departure12:05pm

San Francisco to San Luis Obispo Bus

With Busbud, comparing and booking tickets for a bus from San Francisco to San Luis Obispo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Francisco to San Luis Obispo.

Whether it is cheap bus tickets or more luxurious buses going to San Luis Obispo from San Francisco, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Francisco, US - San Luis Obispo

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
$35
09/12
No data
Today
$47
09/14
No data
09/15
$36
09/16
$34
09/17
$61
09/18
$34
busbud logoThe cheapest trip from San Francisco, US to San Luis Obispo was searched and found on Sep 16, 2025 with a price of $34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Luis Obispo, as early as possible.

You can expect to pay from $34 to $203 for a bus ticket from San Francisco, US to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at $34 which is on 2025-09-16.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Francisco to San Luis Obispo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Francisco to San Luis Obispo.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Francisco to San Luis Obispo.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Francisco to San Luis Obispo.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to San Francisco, US by bus?

Bus from San Luis Obispo to San Francisco, US

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