Find coaches from San Jose, US to Panama City, US

Next departures

Next departures from San Jose to Panama City on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Diridon Station
Panama City Beach StationCheapestFastest

Last refresh of the prices: Last Sunday at 10:32 AM PDT.

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Get from San Jose to Panama City

busbud logoThis route is served by bus only

The journey takes about 2 days, 19 hours 55 minutes, and with fares starting at just US$162, it presents an excellent value for a comfortable ride.

3bus per day
2d 19hAverage duration
3412 kmDistance
85kgCO₂ emissions

Bus San Jose, US to Panama City, US: Trip Overview

Average ticket priceUS$246
Average bus trip duration2d 19h
Number of daily buses3
Earliest bus departure00:55
Distance3411 km
Latest bus departure23:10

San Jose to Panama City Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Jose to Panama City.

Bus service from San Jose to Panama City will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from San Jose, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Jose, US - Panama City, US

  1. How much does a bus ticket from San Jose to Panama City cost?

    The bus ticket price from San Jose to Panama City starts at US$162. The best way to find cheap bus tickets from San Jose to Panama City is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from San Jose to Panama City?

    The average travel time between San Jose and Panama City is around 2d 19h, although the fastest bus will take about 2d 17h. This is the time it takes to travel the 3425 km that separates the two cities.

  3. How many daily bus connections are there between San Jose and Panama City?

    The number of buses from San Jose to Panama City can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Jose to Panama City by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from San Jose to Panama City?

    When taking the bus from San Jose to Panama City, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from San Jose to Panama City?

    Buses travelling between San Jose and Panama City leave from Diridon Station or Santiago Express San Jose and arrive at Panama City Greyhound Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$482
29/10
No data
Today
US$326
31/10
US$233
01/11
No data
02/11
No data
03/11
US$245
04/11
No data
busbud logoThe cheapest trip from San Jose, US to Panama City, US was searched and found on 31 Oct 2025 with a price of US$233

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Jose, US to Panama City, US as early as possible.

You can expect to pay from US$233 to US$482 for a bus ticket from San Jose, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$233, which is on 2025-10-31.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Jose to Panama City but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from San Jose to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Jose to Panama City.

Make a music playlist for your bus ride from San Jose to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to San Jose, US by bus?

Bus from Panama City, US to San Jose, US

Why choose Busbud?

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