Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Diridon Station | Panama City Beach Station | Cheapest | ||||
 | Bus | Diridon Station | Panama City Beach Station | Fastest |
Last refresh of the prices: Last Saturday at 8:46 AM PST.
Get from San Jose to Panama City
The journey takes about 2 days, 20 hours, and with fares starting at just R 2 394, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Jose and Panama City?
Stops in San Jose
- A65 Cahill St., San Jose, CA 95110
- B440 S King rd , an Jose CA 95116
- C
1118 E William St
1118 E William St, San Jose, CA 95116, USA - D
San Jose Bus Stop
100 W San Carlos St, San Jose, CA 95113, USA - E
Tamien Station
Guadalupe Fwy, San Jose, CA 95110, USA - F
Diridon Station
65 Cahill St, San Jose, CA 95110, USA
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Compare bus companies
Frequently asked questions about travelling from San Jose, US to Panama City, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Jose to Panama City?
The cheapest bus tickets from San Jose to Panama City start at R 2 394. The average price for this route is around R 3 365. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Jose to Panama City?
The average bus journey time from San Jose to Panama City is 2d 20h, covering a distance of 3412 km. The fastest bus gets you there in 2d 18h and is operated by Greyhound.
Which bus companies service the San Jose to Panama City route?
What is the earliest and latest departure time for the bus from San Jose to Panama City?
The earliest bus departs from San Jose to Panama City at 00:55. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from San Jose to Panama City?
A bus trip from San Jose to Panama City produces an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Jose to Panama City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from San Jose to Panama City?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from San Jose to Panama City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Jose to Panama City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Jose, US to Panama City, US was searched and found on 20 Dec 2025 with a price of R 5 126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Jose, US to Panama City, US as early as possible.
You can expect to pay from R 5 126 to R 9 856 for a bus ticket from San Jose, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 5 126, which is on 2025-12-20.
